Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002094145> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2002094145 endingPage "275" @default.
- W2002094145 startingPage "271" @default.
- W2002094145 abstract "To study the changes in gene expression in senescent cells we applied the suppression subtractive hybridization of two cDNA pools isolated from human parenchymal kidney cells in the phase of exponential growth and cellular senescence in vitro . In addition to several genes known to be associated with cellular senescence, we identified a new gene, which is overexpressed in senescent kidney parenchymal cells. The full-length cDNA consists of 5226 nucleotides with an open reading frame (ORF) encoding 701 amino acids (Accession number: AJ306929). The gene product has a predicted molecular mass of 77.31 kDa. The ORF of the new gene shows significant homology to P-type ATPase family gene products and therefore was called AFURS1 ( A TPase f amily homolog u p- r egulated in s enescence cells). The consensus sequence phosphorylation site (DKTGTLT) is highly conserved. According to the GenBank database AFURS1 is mapped to the sequence segment NT_005535.3 at chromosomal region 3q26.32 and has 18 exons. The AFURS1 gene might have a role in cellular aging and tumor suppression as well." @default.
- W2002094145 created "2016-06-24" @default.
- W2002094145 creator A5023486650 @default.
- W2002094145 creator A5078143450 @default.
- W2002094145 date "2002-01-01" @default.
- W2002094145 modified "2023-09-23" @default.
- W2002094145 title "Cloning the AFURS1 gene which is up-regulated in senescent human parenchymal kidney cells" @default.
- W2002094145 cites W1807212217 @default.
- W2002094145 cites W1846338561 @default.
- W2002094145 cites W1912742005 @default.
- W2002094145 cites W1968572771 @default.
- W2002094145 cites W1971140237 @default.
- W2002094145 cites W2003217244 @default.
- W2002094145 cites W2004833000 @default.
- W2002094145 cites W2006967054 @default.
- W2002094145 cites W2007772649 @default.
- W2002094145 cites W2036385196 @default.
- W2002094145 cites W2046948008 @default.
- W2002094145 cites W2047330128 @default.
- W2002094145 cites W2049661143 @default.
- W2002094145 cites W2050551830 @default.
- W2002094145 cites W2069408483 @default.
- W2002094145 cites W2077695433 @default.
- W2002094145 cites W2089391247 @default.
- W2002094145 cites W2102064340 @default.
- W2002094145 cites W2104908670 @default.
- W2002094145 cites W2106882534 @default.
- W2002094145 cites W2162390980 @default.
- W2002094145 cites W2168847939 @default.
- W2002094145 cites W256880428 @default.
- W2002094145 doi "https://doi.org/10.1016/s0378-1119(01)00881-2" @default.
- W2002094145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11867234" @default.
- W2002094145 hasPublicationYear "2002" @default.
- W2002094145 type Work @default.
- W2002094145 sameAs 2002094145 @default.
- W2002094145 citedByCount "15" @default.
- W2002094145 countsByYear W20020941452012 @default.
- W2002094145 countsByYear W20020941452013 @default.
- W2002094145 countsByYear W20020941452018 @default.
- W2002094145 countsByYear W20020941452019 @default.
- W2002094145 countsByYear W20020941452020 @default.
- W2002094145 countsByYear W20020941452022 @default.
- W2002094145 crossrefType "journal-article" @default.
- W2002094145 hasAuthorship W2002094145A5023486650 @default.
- W2002094145 hasAuthorship W2002094145A5078143450 @default.
- W2002094145 hasConcept C104317684 @default.
- W2002094145 hasConcept C150194340 @default.
- W2002094145 hasConcept C153911025 @default.
- W2002094145 hasConcept C165525559 @default.
- W2002094145 hasConcept C167625842 @default.
- W2002094145 hasConcept C187882448 @default.
- W2002094145 hasConcept C189482833 @default.
- W2002094145 hasConcept C195286587 @default.
- W2002094145 hasConcept C196436469 @default.
- W2002094145 hasConcept C36823959 @default.
- W2002094145 hasConcept C47289529 @default.
- W2002094145 hasConcept C54355233 @default.
- W2002094145 hasConcept C79029880 @default.
- W2002094145 hasConcept C84597430 @default.
- W2002094145 hasConcept C86803240 @default.
- W2002094145 hasConceptScore W2002094145C104317684 @default.
- W2002094145 hasConceptScore W2002094145C150194340 @default.
- W2002094145 hasConceptScore W2002094145C153911025 @default.
- W2002094145 hasConceptScore W2002094145C165525559 @default.
- W2002094145 hasConceptScore W2002094145C167625842 @default.
- W2002094145 hasConceptScore W2002094145C187882448 @default.
- W2002094145 hasConceptScore W2002094145C189482833 @default.
- W2002094145 hasConceptScore W2002094145C195286587 @default.
- W2002094145 hasConceptScore W2002094145C196436469 @default.
- W2002094145 hasConceptScore W2002094145C36823959 @default.
- W2002094145 hasConceptScore W2002094145C47289529 @default.
- W2002094145 hasConceptScore W2002094145C54355233 @default.
- W2002094145 hasConceptScore W2002094145C79029880 @default.
- W2002094145 hasConceptScore W2002094145C84597430 @default.
- W2002094145 hasConceptScore W2002094145C86803240 @default.
- W2002094145 hasIssue "1-2" @default.
- W2002094145 hasLocation W20020941451 @default.
- W2002094145 hasLocation W20020941452 @default.
- W2002094145 hasOpenAccess W2002094145 @default.
- W2002094145 hasPrimaryLocation W20020941451 @default.
- W2002094145 hasRelatedWork W1464584225 @default.
- W2002094145 hasRelatedWork W1531528770 @default.
- W2002094145 hasRelatedWork W2004746739 @default.
- W2002094145 hasRelatedWork W2089799578 @default.
- W2002094145 hasRelatedWork W2347422362 @default.
- W2002094145 hasRelatedWork W2369816726 @default.
- W2002094145 hasRelatedWork W2375714649 @default.
- W2002094145 hasRelatedWork W2380306570 @default.
- W2002094145 hasRelatedWork W2382593249 @default.
- W2002094145 hasRelatedWork W2390952202 @default.
- W2002094145 hasVolume "283" @default.
- W2002094145 isParatext "false" @default.
- W2002094145 isRetracted "false" @default.
- W2002094145 magId "2002094145" @default.
- W2002094145 workType "article" @default.