FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002097777> ?p ?o ?g. }

• W2002097777 abstract "Forty years ago, after the establishment of coronary care units, a significant decrease in mortality of acute myocardial infarction was noted. Twenty years ago, the break-through of thrombolysis realized once again a significant decrease in mortality. In this study we compare, in a rather small community hospital, the mortality and safety of thrombolytic therapy in acute myocardial infarction with a more conventional, conservative medical therapy. We examined all cases of acute myocardial infarction between 1978 up to 1998 inclusive, concerning treatment and mortality rate after a six month period. To be included in the study, acute myocardial infarction had to fulfill particular inclusion criteria. A total of 1863 cases of acute myocardial infarction were included. The mortality rate of patients with acute myocardial infarction treated with thrombolytic agents was strikingly lower and statistically very significantly different (p < 0.001) in comparison with the mortality rate of patients treated with heparin or coumarine derivatives. The mortality rate dropped from 10.57% in the coumarine group and from 14.95% in the heparin group to 5.41% in the alteplase group, to 4.95% in the anistreplase group and 4.00% in the streptokinase subgroup. The complications directly connected to the treatment did not seem to be different between the five groups, and they were also not more frequent by using thrombolytic agents. In the last 20 years, better preventive measures (life habits, diet, medication) and trials to better control the risk factors have not influenced greatly the average amount of cholesterol in patients with an acute myocardial infarction. Also the percentage of patients with high blood pressure has hardly decreased over the last 20 years. The mortality associated with acute myocardial infarction has decreased significantly with the use of thrombolytics. In most cases, thrombolytics are administered routinely and safely. In this way, they are the first choice therapy for myocardial infarction in smaller hospitals. To obtain excellent coronary patency, thrombolytic agents with a long half-life and with PAI-1 resistance are required in the future. The current measures and medical therapies seem to be insufficient to control the risk factors for coronary atherosclerosis." @default.
• W2002097777 created "2016-06-24" @default.
• W2002097777 creator A5010052465 @default.
• W2002097777 creator A5029563260 @default.
• W2002097777 creator A5038231537 @default.
• W2002097777 creator A5043406848 @default.
• W2002097777 creator A5084827752 @default.
• W2002097777 date "2000-01-01" @default.
• W2002097777 modified "2023-10-03" @default.
• W2002097777 title "Changes in Mortality of Acute Myocardial Infarction as a Function of a Changing Treatment during the last Two Decades" @default.
• W2002097777 cites W1516146552 @default.
• W2002097777 cites W1604564424 @default.
• W2002097777 cites W188646075 @default.
• W2002097777 cites W1964914349 @default.
• W2002097777 cites W1967153357 @default.
• W2002097777 cites W1968582628 @default.
• W2002097777 cites W1971111371 @default.
• W2002097777 cites W1980595836 @default.
• W2002097777 cites W1981946058 @default.
• W2002097777 cites W1997007223 @default.
• W2002097777 cites W1998065289 @default.
• W2002097777 cites W2000037669 @default.
• W2002097777 cites W2001184209 @default.
• W2002097777 cites W2001593915 @default.
• W2002097777 cites W2002253851 @default.
• W2002097777 cites W2005512234 @default.
• W2002097777 cites W2007179245 @default.
• W2002097777 cites W2007516251 @default.
• W2002097777 cites W2010836948 @default.
• W2002097777 cites W2010978404 @default.
• W2002097777 cites W2013262678 @default.
• W2002097777 cites W2027559217 @default.
• W2002097777 cites W2039850335 @default.
• W2002097777 cites W2041812468 @default.
• W2002097777 cites W2044991495 @default.
• W2002097777 cites W2045041228 @default.
• W2002097777 cites W2055644087 @default.
• W2002097777 cites W2058594851 @default.
• W2002097777 cites W2058842760 @default.
• W2002097777 cites W2059175879 @default.
• W2002097777 cites W2069039926 @default.
• W2002097777 cites W2073683490 @default.
• W2002097777 cites W2075971671 @default.
• W2002097777 cites W2079364020 @default.
• W2002097777 cites W2083780918 @default.
• W2002097777 cites W2083860177 @default.
• W2002097777 cites W2086079257 @default.
• W2002097777 cites W2090944577 @default.
• W2002097777 cites W2097352552 @default.
• W2002097777 cites W2102348393 @default.
• W2002097777 cites W2117966472 @default.
• W2002097777 cites W2124458970 @default.
• W2002097777 cites W2126418574 @default.
• W2002097777 cites W2126611770 @default.
• W2002097777 cites W2126728315 @default.
• W2002097777 cites W2131894046 @default.
• W2002097777 cites W2133308986 @default.
• W2002097777 cites W2159170752 @default.
• W2002097777 cites W2170334643 @default.
• W2002097777 cites W2209198020 @default.
• W2002097777 cites W2400662350 @default.
• W2002097777 cites W2404400480 @default.
• W2002097777 cites W2409389348 @default.
• W2002097777 cites W2412634445 @default.
• W2002097777 cites W2412838014 @default.
• W2002097777 cites W2415965900 @default.
• W2002097777 cites W2417135867 @default.
• W2002097777 cites W2418287763 @default.
• W2002097777 cites W2418478951 @default.
• W2002097777 cites W2419672344 @default.
• W2002097777 cites W2425949832 @default.
• W2002097777 cites W2432679485 @default.
• W2002097777 cites W2463102399 @default.
• W2002097777 cites W3134223493 @default.
• W2002097777 cites W63581407 @default.
• W2002097777 cites W2077359997 @default.
• W2002097777 doi "https://doi.org/10.1536/jhj.41.683" @default.
• W2002097777 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11232986" @default.
• W2002097777 hasPublicationYear "2000" @default.
• W2002097777 type Work @default.
• W2002097777 sameAs 2002097777 @default.
• W2002097777 citedByCount "4" @default.
• W2002097777 crossrefType "journal-article" @default.
• W2002097777 hasAuthorship W2002097777A5010052465 @default.
• W2002097777 hasAuthorship W2002097777A5029563260 @default.
• W2002097777 hasAuthorship W2002097777A5038231537 @default.
• W2002097777 hasAuthorship W2002097777A5043406848 @default.
• W2002097777 hasAuthorship W2002097777A5084827752 @default.
• W2002097777 hasBestOaLocation W20020977771 @default.
• W2002097777 hasConcept C126322002 @default.
• W2002097777 hasConcept C164705383 @default.
• W2002097777 hasConcept C179755657 @default.
• W2002097777 hasConcept C2776336681 @default.
• W2002097777 hasConcept C2777557582 @default.
• W2002097777 hasConcept C2779581417 @default.
• W2002097777 hasConcept C500558357 @default.
• W2002097777 hasConcept C71924100 @default.
• W2002097777 hasConceptScore W2002097777C126322002 @default.
• W2002097777 hasConceptScore W2002097777C164705383 @default.
• W2002097777 hasConceptScore W2002097777C179755657 @default.

• next