Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002106711> ?p ?o ?g. }
- W2002106711 endingPage "665" @default.
- W2002106711 startingPage "659" @default.
- W2002106711 abstract "This work examines the effect of delivering a DNA plasmid encoding murine erythropoietin (pVRmEpo) to BALB/c mice by gene gun. Whereas intramuscular injection elicits a rise in hematocrit persisting > 8 months, intradermal delivery triggers the dose-dependent secretion of biologically active erythropoietin (Epo) for 1 month. Repeated administration of pVRmEpo by gene gun elicits a stable increase in hematocrit. The source of the Epo produced following gene gun delivery was analyzed by periodically grafting the site of injection onto naive recipients. Results indicate that both stationary cells (presumably keratinocytes) and migratory (presumably dendritic) cells were transfected and secreted biologically active Epo in vivo . Gene gun administration of plasmid DNA appears to be safe, and provides an additional strategy for achieving the regulated secretion of an exogenous gene product." @default.
- W2002106711 created "2016-06-24" @default.
- W2002106711 creator A5003246603 @default.
- W2002106711 creator A5039225909 @default.
- W2002106711 creator A5043470455 @default.
- W2002106711 creator A5047442341 @default.
- W2002106711 creator A5051325450 @default.
- W2002106711 date "1999-03-01" @default.
- W2002106711 modified "2023-09-24" @default.
- W2002106711 title "Safe and Effective Regulation of Hematocrit by Gene Gun Administration of an Erythropoietin-Encoding DNA Plasmid" @default.
- W2002106711 cites W1553465751 @default.
- W2002106711 cites W1791948424 @default.
- W2002106711 cites W1965172479 @default.
- W2002106711 cites W1969918693 @default.
- W2002106711 cites W1970708694 @default.
- W2002106711 cites W1974877896 @default.
- W2002106711 cites W1982711578 @default.
- W2002106711 cites W1985505368 @default.
- W2002106711 cites W1995315280 @default.
- W2002106711 cites W2002022916 @default.
- W2002106711 cites W2011190969 @default.
- W2002106711 cites W2014495927 @default.
- W2002106711 cites W2022698852 @default.
- W2002106711 cites W2023506304 @default.
- W2002106711 cites W2024093530 @default.
- W2002106711 cites W2029426142 @default.
- W2002106711 cites W2031598154 @default.
- W2002106711 cites W2034511195 @default.
- W2002106711 cites W2036650398 @default.
- W2002106711 cites W2040493614 @default.
- W2002106711 cites W2041805971 @default.
- W2002106711 cites W2046573487 @default.
- W2002106711 cites W2062513117 @default.
- W2002106711 cites W2063711724 @default.
- W2002106711 cites W2065153598 @default.
- W2002106711 cites W2065849927 @default.
- W2002106711 cites W2068441823 @default.
- W2002106711 cites W2069503376 @default.
- W2002106711 cites W2070426326 @default.
- W2002106711 cites W2072831451 @default.
- W2002106711 cites W2076462595 @default.
- W2002106711 cites W2084742882 @default.
- W2002106711 cites W2090864647 @default.
- W2002106711 cites W2095221154 @default.
- W2002106711 cites W2100545183 @default.
- W2002106711 cites W2143399845 @default.
- W2002106711 cites W2147851449 @default.
- W2002106711 cites W2156521514 @default.
- W2002106711 cites W2400034939 @default.
- W2002106711 cites W2419776913 @default.
- W2002106711 doi "https://doi.org/10.1089/10430349950018733" @default.
- W2002106711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10094209" @default.
- W2002106711 hasPublicationYear "1999" @default.
- W2002106711 type Work @default.
- W2002106711 sameAs 2002106711 @default.
- W2002106711 citedByCount "25" @default.
- W2002106711 countsByYear W20021067112013 @default.
- W2002106711 countsByYear W20021067112015 @default.
- W2002106711 crossrefType "journal-article" @default.
- W2002106711 hasAuthorship W2002106711A5003246603 @default.
- W2002106711 hasAuthorship W2002106711A5039225909 @default.
- W2002106711 hasAuthorship W2002106711A5043470455 @default.
- W2002106711 hasAuthorship W2002106711A5047442341 @default.
- W2002106711 hasAuthorship W2002106711A5051325450 @default.
- W2002106711 hasConcept C104317684 @default.
- W2002106711 hasConcept C111599444 @default.
- W2002106711 hasConcept C134018914 @default.
- W2002106711 hasConcept C135983454 @default.
- W2002106711 hasConcept C153911025 @default.
- W2002106711 hasConcept C167508917 @default.
- W2002106711 hasConcept C168112101 @default.
- W2002106711 hasConcept C195856716 @default.
- W2002106711 hasConcept C203014093 @default.
- W2002106711 hasConcept C22744801 @default.
- W2002106711 hasConcept C2778534260 @default.
- W2002106711 hasConcept C2780959883 @default.
- W2002106711 hasConcept C49039625 @default.
- W2002106711 hasConcept C54009773 @default.
- W2002106711 hasConcept C54355233 @default.
- W2002106711 hasConcept C71924100 @default.
- W2002106711 hasConcept C86803240 @default.
- W2002106711 hasConcept C98274493 @default.
- W2002106711 hasConceptScore W2002106711C104317684 @default.
- W2002106711 hasConceptScore W2002106711C111599444 @default.
- W2002106711 hasConceptScore W2002106711C134018914 @default.
- W2002106711 hasConceptScore W2002106711C135983454 @default.
- W2002106711 hasConceptScore W2002106711C153911025 @default.
- W2002106711 hasConceptScore W2002106711C167508917 @default.
- W2002106711 hasConceptScore W2002106711C168112101 @default.
- W2002106711 hasConceptScore W2002106711C195856716 @default.
- W2002106711 hasConceptScore W2002106711C203014093 @default.
- W2002106711 hasConceptScore W2002106711C22744801 @default.
- W2002106711 hasConceptScore W2002106711C2778534260 @default.
- W2002106711 hasConceptScore W2002106711C2780959883 @default.
- W2002106711 hasConceptScore W2002106711C49039625 @default.
- W2002106711 hasConceptScore W2002106711C54009773 @default.
- W2002106711 hasConceptScore W2002106711C54355233 @default.
- W2002106711 hasConceptScore W2002106711C71924100 @default.