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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002120431> ?p ?o ?g. }

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• W2002120431 abstract "The synthesis of a series of methoxy bearing 2,2-dimethyl-2H-1-benzopyrans have been achieved for testing as potassium channel activators. The synthesis involves formation of 6-cyano-8-methoxy-2,2-dimethyl-2H-1-benzopyran from vanillin, epoxidation, then ring opening of the epoxide with nitrogen nucleophiles to produce the new benzopyrans. Biological testing showed a dramatic decrease in activity thus revealing an important site of activity in this class of compounds." @default.
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• W2002120431 date "2003-04-01" @default.
• W2002120431 modified "2023-10-11" @default.
• W2002120431 title "Potassium channel activators based on the benzopyran substructure: synthesis and activity of the C-8 substituent" @default.
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• W2002120431 doi "https://doi.org/10.1016/s0968-0896(03)00058-0" @default.
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