Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002123911> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2002123911 abstract "Post-translational modifications pegged on to the N-terminal tails of the nucleosomes core histone proteins determine the transcriptional activity of that chromosomal region leading to the histone code hypothesis. We rely on recently produced experimental data on genome-wide maps of chromatin state to derive computational models delineating the hidden patterns of post-translational modifications. We use support vector machines to model and predict post-translational modification state of the histones using a diverse set of features. The classification results on the human CD-4+ T-cells by five-fold cross-validation show promising results. Our analysis reveals better classification accuracy when employing chromosome-specific classifiers. Finally, we show how computational models can be used to provide an initial estimate of the chromatin state and its effect on DNA loci." @default.
- W2002123911 created "2016-06-24" @default.
- W2002123911 creator A5017119312 @default.
- W2002123911 creator A5048052017 @default.
- W2002123911 creator A5059087647 @default.
- W2002123911 date "2009-05-01" @default.
- W2002123911 modified "2023-09-23" @default.
- W2002123911 title "Machine learning approach for classifying histone modifications" @default.
- W2002123911 cites W1965262464 @default.
- W2002123911 cites W1979137652 @default.
- W2002123911 cites W2007684630 @default.
- W2002123911 cites W2015416439 @default.
- W2002123911 cites W2081195534 @default.
- W2002123911 cites W2096083625 @default.
- W2002123911 cites W2108871359 @default.
- W2002123911 cites W2134314200 @default.
- W2002123911 cites W2153007310 @default.
- W2002123911 cites W2153635508 @default.
- W2002123911 doi "https://doi.org/10.1109/gensips.2009.5174355" @default.
- W2002123911 hasPublicationYear "2009" @default.
- W2002123911 type Work @default.
- W2002123911 sameAs 2002123911 @default.
- W2002123911 citedByCount "0" @default.
- W2002123911 crossrefType "proceedings-article" @default.
- W2002123911 hasAuthorship W2002123911A5017119312 @default.
- W2002123911 hasAuthorship W2002123911A5048052017 @default.
- W2002123911 hasAuthorship W2002123911A5059087647 @default.
- W2002123911 hasConcept C10058791 @default.
- W2002123911 hasConcept C104317684 @default.
- W2002123911 hasConcept C12267149 @default.
- W2002123911 hasConcept C141231307 @default.
- W2002123911 hasConcept C154945302 @default.
- W2002123911 hasConcept C177264268 @default.
- W2002123911 hasConcept C199360897 @default.
- W2002123911 hasConcept C30481170 @default.
- W2002123911 hasConcept C41008148 @default.
- W2002123911 hasConcept C54355233 @default.
- W2002123911 hasConcept C552990157 @default.
- W2002123911 hasConcept C64927066 @default.
- W2002123911 hasConcept C70721500 @default.
- W2002123911 hasConcept C83640560 @default.
- W2002123911 hasConcept C84772758 @default.
- W2002123911 hasConcept C86803240 @default.
- W2002123911 hasConceptScore W2002123911C10058791 @default.
- W2002123911 hasConceptScore W2002123911C104317684 @default.
- W2002123911 hasConceptScore W2002123911C12267149 @default.
- W2002123911 hasConceptScore W2002123911C141231307 @default.
- W2002123911 hasConceptScore W2002123911C154945302 @default.
- W2002123911 hasConceptScore W2002123911C177264268 @default.
- W2002123911 hasConceptScore W2002123911C199360897 @default.
- W2002123911 hasConceptScore W2002123911C30481170 @default.
- W2002123911 hasConceptScore W2002123911C41008148 @default.
- W2002123911 hasConceptScore W2002123911C54355233 @default.
- W2002123911 hasConceptScore W2002123911C552990157 @default.
- W2002123911 hasConceptScore W2002123911C64927066 @default.
- W2002123911 hasConceptScore W2002123911C70721500 @default.
- W2002123911 hasConceptScore W2002123911C83640560 @default.
- W2002123911 hasConceptScore W2002123911C84772758 @default.
- W2002123911 hasConceptScore W2002123911C86803240 @default.
- W2002123911 hasLocation W20021239111 @default.
- W2002123911 hasOpenAccess W2002123911 @default.
- W2002123911 hasPrimaryLocation W20021239111 @default.
- W2002123911 hasRelatedWork W2013720323 @default.
- W2002123911 hasRelatedWork W2036158314 @default.
- W2002123911 hasRelatedWork W2100369840 @default.
- W2002123911 hasRelatedWork W2106090146 @default.
- W2002123911 hasRelatedWork W2119000216 @default.
- W2002123911 hasRelatedWork W2166762931 @default.
- W2002123911 hasRelatedWork W2729636480 @default.
- W2002123911 hasRelatedWork W3128380517 @default.
- W2002123911 hasRelatedWork W4210706400 @default.
- W2002123911 hasRelatedWork W4214808186 @default.
- W2002123911 isParatext "false" @default.
- W2002123911 isRetracted "false" @default.
- W2002123911 magId "2002123911" @default.
- W2002123911 workType "article" @default.