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- W2002126009 abstract "The action of [Co(NH3)6]Cl3 on poly(dGdC) · poly(dGdC) can lead to a series of consecutive reactions, in which B-DNA is first converted to Z-DNA [M. Behe and G. Felsenfeld (1981) Proc. Natl. Acad. Sci USA 78, 1619–1623], which in turn is transformed into an unidentified conformer that we tentatively call “U”, and finally the highly associated anisotropic ψ-DNA is produced. Conditions are given under which the sequence B ⇄ Z ⇄ “U” ψ(+) can be stopped at any point in the direction from left to right. The reverse processes, from right to left, occur when ψ(+) or “U”-DNA are treated with various amounts of salt concentrations and lowering temperature. Thus it is demonstrated that four conformers of poly(dGdC) · poly(dGdC) are readily interconvertible, and that Z-DNA and “U” conformers are intermediates in the reversible transformations of B- and ψ-DNA." @default.
- W2002126009 created "2016-06-24" @default.
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- W2002126009 date "1988-09-01" @default.
- W2002126009 modified "2023-09-23" @default.
- W2002126009 title "Metal-Induced sequential transitions among DNA conformations" @default.
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- W2002126009 doi "https://doi.org/10.1002/bip.360270908" @default.
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