Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002127516> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2002127516 endingPage "314" @default.
- W2002127516 startingPage "309" @default.
- W2002127516 abstract "Binding of high-Mr kininogen and factor XII/factor XIIa to phospholipids coated on to polystyrene microtiter plates was investigated by ELISA. Both high-Mr kininogen and factor XII/factor XIIa bound specifically to the phospholipid surface. Binding was observed to negatively charged phospholipids only. The binding of high-Mr kininogen was not affected by the presence of zinc ions. At a surface concentration of 20% phosphatidylinositol phosphate in phosphatidylcholine a dissociation constant (kD) of 10 nM for the binding of high-Mr kininogen was calculated. The amount of bound purified α-factor XIIa could be increased 4–5-fold in the presence of zinc ions. The lowest zinc ion concentration giving maximal binding was 0.1 mM. The binding of α-factor XIIa was inhibited by high-Mr kininogen. Independent of the presence of zinc ions or high-Mr kininogen, a kD of 7.9 nM was calculated for α-factor XIIa binding. The binding of prekallikrein was dependent upon the presence and the concentration of high-Mr kininogen. In plasma containing aprotinin, the binding of high-Mr kininogen was apparently inhibited in the presence of zinc ions, which was a prerequisite for the binding of factor XII. This apparently inhibitory effect of zinc ions on the binding of high-Mr kininogen was probably due to the increased binding of factor XII, which displaced high-Mr kininogen." @default.
- W2002127516 created "2016-06-24" @default.
- W2002127516 creator A5084847190 @default.
- W2002127516 creator A5090713365 @default.
- W2002127516 date "1991-04-01" @default.
- W2002127516 modified "2023-09-24" @default.
- W2002127516 title "Zinc ions promote the binding of factor XII/factor XIIA to acidic phospholipids but have no effect on the binding of high-Mr kininogen" @default.
- W2002127516 cites W1599155589 @default.
- W2002127516 cites W1917139283 @default.
- W2002127516 cites W1939766220 @default.
- W2002127516 cites W1944402964 @default.
- W2002127516 cites W1985342306 @default.
- W2002127516 cites W1988770415 @default.
- W2002127516 cites W2005060011 @default.
- W2002127516 cites W2011532980 @default.
- W2002127516 cites W2014277394 @default.
- W2002127516 cites W2014279568 @default.
- W2002127516 cites W2041911603 @default.
- W2002127516 cites W2051140751 @default.
- W2002127516 cites W2053537943 @default.
- W2002127516 cites W2055667942 @default.
- W2002127516 cites W2066149593 @default.
- W2002127516 cites W2067614175 @default.
- W2002127516 cites W2092462079 @default.
- W2002127516 cites W4230354809 @default.
- W2002127516 doi "https://doi.org/10.1111/j.1432-1033.1991.tb15912.x" @default.
- W2002127516 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2026153" @default.
- W2002127516 hasPublicationYear "1991" @default.
- W2002127516 type Work @default.
- W2002127516 sameAs 2002127516 @default.
- W2002127516 citedByCount "10" @default.
- W2002127516 crossrefType "journal-article" @default.
- W2002127516 hasAuthorship W2002127516A5084847190 @default.
- W2002127516 hasAuthorship W2002127516A5090713365 @default.
- W2002127516 hasConcept C107824862 @default.
- W2002127516 hasConcept C126322002 @default.
- W2002127516 hasConcept C152328610 @default.
- W2002127516 hasConcept C178790620 @default.
- W2002127516 hasConcept C181199279 @default.
- W2002127516 hasConcept C185592680 @default.
- W2002127516 hasConcept C2777167447 @default.
- W2002127516 hasConcept C2777902427 @default.
- W2002127516 hasConcept C2778382381 @default.
- W2002127516 hasConcept C2778918659 @default.
- W2002127516 hasConcept C2781317560 @default.
- W2002127516 hasConcept C41625074 @default.
- W2002127516 hasConcept C52853521 @default.
- W2002127516 hasConcept C535196362 @default.
- W2002127516 hasConcept C55493867 @default.
- W2002127516 hasConcept C71924100 @default.
- W2002127516 hasConceptScore W2002127516C107824862 @default.
- W2002127516 hasConceptScore W2002127516C126322002 @default.
- W2002127516 hasConceptScore W2002127516C152328610 @default.
- W2002127516 hasConceptScore W2002127516C178790620 @default.
- W2002127516 hasConceptScore W2002127516C181199279 @default.
- W2002127516 hasConceptScore W2002127516C185592680 @default.
- W2002127516 hasConceptScore W2002127516C2777167447 @default.
- W2002127516 hasConceptScore W2002127516C2777902427 @default.
- W2002127516 hasConceptScore W2002127516C2778382381 @default.
- W2002127516 hasConceptScore W2002127516C2778918659 @default.
- W2002127516 hasConceptScore W2002127516C2781317560 @default.
- W2002127516 hasConceptScore W2002127516C41625074 @default.
- W2002127516 hasConceptScore W2002127516C52853521 @default.
- W2002127516 hasConceptScore W2002127516C535196362 @default.
- W2002127516 hasConceptScore W2002127516C55493867 @default.
- W2002127516 hasConceptScore W2002127516C71924100 @default.
- W2002127516 hasIssue "2" @default.
- W2002127516 hasLocation W20021275161 @default.
- W2002127516 hasLocation W20021275162 @default.
- W2002127516 hasOpenAccess W2002127516 @default.
- W2002127516 hasPrimaryLocation W20021275161 @default.
- W2002127516 hasRelatedWork W1888682425 @default.
- W2002127516 hasRelatedWork W1982170684 @default.
- W2002127516 hasRelatedWork W1990266683 @default.
- W2002127516 hasRelatedWork W1996282461 @default.
- W2002127516 hasRelatedWork W2053692752 @default.
- W2002127516 hasRelatedWork W2058162127 @default.
- W2002127516 hasRelatedWork W2087037963 @default.
- W2002127516 hasRelatedWork W2175700465 @default.
- W2002127516 hasRelatedWork W2340244022 @default.
- W2002127516 hasRelatedWork W2968890440 @default.
- W2002127516 hasVolume "197" @default.
- W2002127516 isParatext "false" @default.
- W2002127516 isRetracted "false" @default.
- W2002127516 magId "2002127516" @default.
- W2002127516 workType "article" @default.