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- W2002129434 abstract "We report here the synthesis of heparin–polynitroxide derivatives (HPNs) in which nitroxide moieties are linked either to uronic acid or glycosamine residues of the heparin macromolecule. HPNs have low anticoagulant activity, possess superoxide scavenging properties, bind to the vascular endothelium/extra-cellular matrix and can be detected by EPR and MRI techniques. As the vascular wall-targeted redox-active paramagnetic compounds, HPNs may have both diagnostic (molecular MRI) and therapeutic (ecSOD mimics) applications." @default.
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- W2002129434 date "2012-12-01" @default.
- W2002129434 modified "2023-09-30" @default.
- W2002129434 title "Heparin–polynitroxides: Synthesis and preliminary evaluation as cardiovascular EPR/MR imaging probes and extracellular space-targeted antioxidants" @default.
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- W2002129434 doi "https://doi.org/10.1016/j.ejmech.2012.09.028" @default.
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