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- W2002133521 abstract "1. 1. Rats treated with phosphoramidon (an enkephalinase-inhibitor 250 μg, i.c.v.), morphine (20 μg i.c.v.) or subjected to cold-water-swim (CWS, animals forced to swim in water at 5°C for 5 min) showed consistent analgesia. 2. 2. The antinociceptive effect of phosphoramidon, morphine and CWS was antagonised by REM sleep deprivation (REMSD). 3. 3. It is suggested that normal duration of REM sleep is of importance for the anti-nociceptive activity of endogenous and exogenous opiates." @default.
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- W2002133521 date "1984-01-01" @default.
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- W2002133521 title "REM sleep deprivation decreases the antinociceptive property of enkephalinase-inhibition, morphine and cold-water-swim" @default.
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- W2002133521 doi "https://doi.org/10.1016/0306-3623(84)90170-8" @default.
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