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- W2002134558 abstract "Abstract Amyloidosis is one of the human diseases that can be studied in animal models. Kuczynski, 1 the pioneer in the field of experimental amyloidosis, used casein to induce amyloidosis in mice in 1923. Subsequently, this method has been widely used by investigators interested in amyloid research, and the Kuczynski method is the most popular and easily reproducible model for induction of reactive (secondary) systemic amyloidosis. The availability of such animal models has greatly advanced our understanding of the reactive systemic amyloidosis. In addition, these models are quite comparable with human reactive amyloidosis as shown by histologic, electron microscopic, immunologic, and biochemical studies; however, there is still no animal model for the primary cutaneous amyloidoses, and animal models for amyloidosis other than AA-type are also scarce." @default.
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- W2002134558 date "1990-04-01" @default.
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- W2002134558 title "Animal models for amyloidosis" @default.
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- W2002134558 doi "https://doi.org/10.1016/0738-081x(90)90093-g" @default.
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