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• W2002143298 abstract "Rabbit antithymocyte globulin (Thymoglobulin ® ) is commonly used as graft-versus-host disease (GvHD) prophylaxis. Since we found similar total CD8 T cell numbers in patients with and without Thymoglobulin ® therapy within the first six months after allogeneic hematopoietic stem cell transplantation, we have analyzed the reconstitution of the CD8 T cell compartment in detail. After T cell-depletion, higher and more sustained proliferative capacity of memory CD8 T cells resulted in their rapid expansion, whereas the fraction of naive CD8 T cells decreased. Importantly, this shift towards effector memory CD8 T cells did not accelerate the incidence of GvHD." @default.
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• W2002143298 date "2013-01-01" @default.
• W2002143298 modified "2023-10-02" @default.
• W2002143298 title "Rabbit antithymocyte globulin induces rapid expansion of effector memory CD8 T cells without accelerating acute graft versus host disease" @default.
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• W2002143298 doi "https://doi.org/10.1016/j.lrr.2013.09.001" @default.
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