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- W2002156973 abstract "Abstract Lithogenic diet, casein and apple fiber diets were fed to hamsters for 3-5 weeks. For control group, animals were fed on normal Purina chow without any supplement. The cholesterol lowering effect of lithogenic diet, casein and apple diets were compared. After dietary regimen, animals were screened for any gall stone formation. The isolated liver microsomes were separated from animals and tested for the cholesterol-7α Hydroxylase (CH) enzyme activity measurement in all three groups. The control animals did not show any gall stone formation and their CH enzyme activities were normal. The lithogenic diet showed significantly enhanced CH enzyme activities while animals fed on casein and apple diet regimen showed moderate increase in microsomal CH enzyme activity indicated cholesterol lowering in liver. In conclusion, cholesterol 7α hydroxylase may be a biomarker of cholesterol status in the body and microsomal CH enzyme may be lowered down after treatment of casein and apple diets." @default.
- W2002156973 created "2016-06-24" @default.
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- W2002156973 date "2010-02-12" @default.
- W2002156973 modified "2023-09-27" @default.
- W2002156973 title "Comparison of Cholesterol Lowering Diets: Apple, Casein Cytochrom P450 protein and Cholesterol 7α Hydroxylase Activities in Hamsters" @default.
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- W2002156973 doi "https://doi.org/10.1038/npre.2010.4205.1" @default.
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