Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002157609> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2002157609 endingPage "182" @default.
- W2002157609 startingPage "178" @default.
- W2002157609 abstract "Verapamil inhibited Na+-dependent uptake of serotonin (5-HT) by bovine pulmonary artery endothelial cells in culture both exposed to room air and stimulated by prior exposure to anoxia. The effect of verapamil occurred even in the absence of Ca2+ from the assay medium. Although absence of Ca2+ from the medium moderately reduced 5-HT uptake, stimulation of uptake was nevertheless observed for cells previously exposed to anoxia. Verapamil altered the Km, but not the Vmax, of 5-HT uptake. There was no change in 45Ca2+ uptake or release by cells previously exposed to anoxia as compared to those exposed to room air and verapamil did not influence 45Ca2+ fluxes by either set of cells. It is concluded that verapamil inhibits 5-HT uptake by endothelial cells through a mechanism other than Ca2+ channel blockade; the results are consistent with competitive inhibition of a 5-HT carrier. The stimulatory effect of anoxia on 5-HT uptake does not occur through a change in Ca2+ fluxes." @default.
- W2002157609 created "2016-06-24" @default.
- W2002157609 creator A5051301255 @default.
- W2002157609 creator A5059196291 @default.
- W2002157609 creator A5082897220 @default.
- W2002157609 creator A5089026219 @default.
- W2002157609 date "1987-07-01" @default.
- W2002157609 modified "2023-09-27" @default.
- W2002157609 title "Verapamil inhibits serotonin uptake of endothelial cells in culture by a mechanism unrelated to Ca2+ channel blockade" @default.
- W2002157609 cites W1527372023 @default.
- W2002157609 cites W1775749144 @default.
- W2002157609 cites W1972311726 @default.
- W2002157609 cites W1997513772 @default.
- W2002157609 cites W2001756863 @default.
- W2002157609 cites W2004766346 @default.
- W2002157609 cites W2018161151 @default.
- W2002157609 cites W2037369226 @default.
- W2002157609 cites W2060486276 @default.
- W2002157609 cites W2117796487 @default.
- W2002157609 cites W2262217076 @default.
- W2002157609 cites W2344483478 @default.
- W2002157609 cites W2500633109 @default.
- W2002157609 doi "https://doi.org/10.1002/jcp.1041320126" @default.
- W2002157609 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3597552" @default.
- W2002157609 hasPublicationYear "1987" @default.
- W2002157609 type Work @default.
- W2002157609 sameAs 2002157609 @default.
- W2002157609 citedByCount "13" @default.
- W2002157609 crossrefType "journal-article" @default.
- W2002157609 hasAuthorship W2002157609A5051301255 @default.
- W2002157609 hasAuthorship W2002157609A5059196291 @default.
- W2002157609 hasAuthorship W2002157609A5082897220 @default.
- W2002157609 hasAuthorship W2002157609A5089026219 @default.
- W2002157609 hasConcept C126322002 @default.
- W2002157609 hasConcept C134018914 @default.
- W2002157609 hasConcept C170493617 @default.
- W2002157609 hasConcept C185592680 @default.
- W2002157609 hasConcept C24998067 @default.
- W2002157609 hasConcept C2775864247 @default.
- W2002157609 hasConcept C2777022698 @default.
- W2002157609 hasConcept C2778468042 @default.
- W2002157609 hasConcept C519063684 @default.
- W2002157609 hasConcept C55493867 @default.
- W2002157609 hasConcept C71924100 @default.
- W2002157609 hasConcept C86803240 @default.
- W2002157609 hasConcept C98274493 @default.
- W2002157609 hasConceptScore W2002157609C126322002 @default.
- W2002157609 hasConceptScore W2002157609C134018914 @default.
- W2002157609 hasConceptScore W2002157609C170493617 @default.
- W2002157609 hasConceptScore W2002157609C185592680 @default.
- W2002157609 hasConceptScore W2002157609C24998067 @default.
- W2002157609 hasConceptScore W2002157609C2775864247 @default.
- W2002157609 hasConceptScore W2002157609C2777022698 @default.
- W2002157609 hasConceptScore W2002157609C2778468042 @default.
- W2002157609 hasConceptScore W2002157609C519063684 @default.
- W2002157609 hasConceptScore W2002157609C55493867 @default.
- W2002157609 hasConceptScore W2002157609C71924100 @default.
- W2002157609 hasConceptScore W2002157609C86803240 @default.
- W2002157609 hasConceptScore W2002157609C98274493 @default.
- W2002157609 hasIssue "1" @default.
- W2002157609 hasLocation W20021576091 @default.
- W2002157609 hasLocation W20021576092 @default.
- W2002157609 hasOpenAccess W2002157609 @default.
- W2002157609 hasPrimaryLocation W20021576091 @default.
- W2002157609 hasRelatedWork W1978618357 @default.
- W2002157609 hasRelatedWork W2025590009 @default.
- W2002157609 hasRelatedWork W2027834137 @default.
- W2002157609 hasRelatedWork W2034768996 @default.
- W2002157609 hasRelatedWork W2054992011 @default.
- W2002157609 hasRelatedWork W2064416809 @default.
- W2002157609 hasRelatedWork W2076192765 @default.
- W2002157609 hasRelatedWork W2128286595 @default.
- W2002157609 hasRelatedWork W2145260320 @default.
- W2002157609 hasRelatedWork W2170990871 @default.
- W2002157609 hasVolume "132" @default.
- W2002157609 isParatext "false" @default.
- W2002157609 isRetracted "false" @default.
- W2002157609 magId "2002157609" @default.
- W2002157609 workType "article" @default.