FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002160983> ?p ?o ?g. }

• W2002160983 endingPage "151" @default.
• W2002160983 startingPage "145" @default.
• W2002160983 abstract "Remote preconditioning is a phenomenon in which brief episodes of ischemia and reperfusion to remote organs protect the target organ against sustained ischemia/reperfusion (I/R)-induced injury. Protective effects of remote aortic preconditioning (RAPC) are well established in the heart, but their mechanisms still remain to be elucidated.This study has been designed to investigate the possible involvement of α-1-adrenergic receptor (AR) and K(ATP) channels in cardio-protective effect of RAPC in isolated rat heart.Four episodes of ischemia and reperfusion, each comprising of 5 min occlusion and 5 min reperfusion, were used to produce RAPC. Isolated perfused rat heart was subjected to global ischemia for 30 min followed by reperfusion for 120 min. Coronary effluent was analyzed for LDH and CK-MB release to assess the degree of cardiac injury. Myocardial infarct size was estimated macroscopically using TTC staining.Phenylephrine (20 μ/kg i.p.), as α-1-AR agonist, was noted to produce RAPC-like cardio-protection. However, administration of glibenclamide concomitantly or prior to phenylephrine abolished cardioprotection. Moreover, prazocin (1 mg/kg. i.p), as α-1-AR antagonist and glibenclamide (1 mg/kg i.p), a K(ATP) channel blocker, abolished the cardioprotective effect of RAPC.These data provide the evidence that α-1-AR activation involved in cardioprotective effect of RAPC-mediated trough opening of K(ATP) channels." @default.
• W2002160983 created "2016-06-24" @default.
• W2002160983 creator A5028915928 @default.
• W2002160983 creator A5030172014 @default.
• W2002160983 creator A5036360503 @default.
• W2002160983 creator A5036385538 @default.
• W2002160983 creator A5090410869 @default.
• W2002160983 date "2010-07-01" @default.
• W2002160983 modified "2023-10-12" @default.
• W2002160983 title "Possible involvement of α1-adrenergic receptor and KATP channels in cardioprotective effect of remote aortic preconditioning in isolated rat heart" @default.
• W2002160983 cites W1516804629 @default.
• W2002160983 cites W1973280197 @default.
• W2002160983 cites W1991117742 @default.
• W2002160983 cites W1991420860 @default.
• W2002160983 cites W1994807395 @default.
• W2002160983 cites W2002179621 @default.
• W2002160983 cites W2002651270 @default.
• W2002160983 cites W2007115581 @default.
• W2002160983 cites W2015670412 @default.
• W2002160983 cites W2021949562 @default.
• W2002160983 cites W2022473516 @default.
• W2002160983 cites W2039548797 @default.
• W2002160983 cites W2043790508 @default.
• W2002160983 cites W2044406716 @default.
• W2002160983 cites W2047763109 @default.
• W2002160983 cites W2048407964 @default.
• W2002160983 cites W2059328843 @default.
• W2002160983 cites W2063177247 @default.
• W2002160983 cites W2066800617 @default.
• W2002160983 cites W2081446252 @default.
• W2002160983 cites W2082648108 @default.
• W2002160983 cites W2095566192 @default.
• W2002160983 cites W2111047732 @default.
• W2002160983 cites W2112334970 @default.
• W2002160983 cites W2136556999 @default.
• W2002160983 cites W2139834613 @default.
• W2002160983 cites W2146217294 @default.
• W2002160983 cites W2146323276 @default.
• W2002160983 cites W2155748853 @default.
• W2002160983 cites W2171196215 @default.
• W2002160983 cites W2443248231 @default.
• W2002160983 doi "https://doi.org/10.4103/0975-3583.70917" @default.
• W2002160983 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2982203" @default.
• W2002160983 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21187869" @default.
• W2002160983 hasPublicationYear "2010" @default.
• W2002160983 type Work @default.
• W2002160983 sameAs 2002160983 @default.
• W2002160983 citedByCount "20" @default.
• W2002160983 countsByYear W20021609832012 @default.
• W2002160983 countsByYear W20021609832013 @default.
• W2002160983 countsByYear W20021609832014 @default.
• W2002160983 countsByYear W20021609832015 @default.
• W2002160983 countsByYear W20021609832016 @default.
• W2002160983 countsByYear W20021609832017 @default.
• W2002160983 countsByYear W20021609832018 @default.
• W2002160983 countsByYear W20021609832019 @default.
• W2002160983 crossrefType "journal-article" @default.
• W2002160983 hasAuthorship W2002160983A5028915928 @default.
• W2002160983 hasAuthorship W2002160983A5030172014 @default.
• W2002160983 hasAuthorship W2002160983A5036360503 @default.
• W2002160983 hasAuthorship W2002160983A5036385538 @default.
• W2002160983 hasAuthorship W2002160983A5090410869 @default.
• W2002160983 hasBestOaLocation W20021609831 @default.
• W2002160983 hasConcept C126322002 @default.
• W2002160983 hasConcept C134018914 @default.
• W2002160983 hasConcept C164705383 @default.
• W2002160983 hasConcept C170493617 @default.
• W2002160983 hasConcept C2776885963 @default.
• W2002160983 hasConcept C2777952589 @default.
• W2002160983 hasConcept C2778938600 @default.
• W2002160983 hasConcept C2779311647 @default.
• W2002160983 hasConcept C2779676291 @default.
• W2002160983 hasConcept C2779768347 @default.
• W2002160983 hasConcept C2780114680 @default.
• W2002160983 hasConcept C42219234 @default.
• W2002160983 hasConcept C541997718 @default.
• W2002160983 hasConcept C555293320 @default.
• W2002160983 hasConcept C71924100 @default.
• W2002160983 hasConcept C84393581 @default.
• W2002160983 hasConcept C98274493 @default.
• W2002160983 hasConceptScore W2002160983C126322002 @default.
• W2002160983 hasConceptScore W2002160983C134018914 @default.
• W2002160983 hasConceptScore W2002160983C164705383 @default.
• W2002160983 hasConceptScore W2002160983C170493617 @default.
• W2002160983 hasConceptScore W2002160983C2776885963 @default.
• W2002160983 hasConceptScore W2002160983C2777952589 @default.
• W2002160983 hasConceptScore W2002160983C2778938600 @default.
• W2002160983 hasConceptScore W2002160983C2779311647 @default.
• W2002160983 hasConceptScore W2002160983C2779676291 @default.
• W2002160983 hasConceptScore W2002160983C2779768347 @default.
• W2002160983 hasConceptScore W2002160983C2780114680 @default.
• W2002160983 hasConceptScore W2002160983C42219234 @default.
• W2002160983 hasConceptScore W2002160983C541997718 @default.
• W2002160983 hasConceptScore W2002160983C555293320 @default.
• W2002160983 hasConceptScore W2002160983C71924100 @default.
• W2002160983 hasConceptScore W2002160983C84393581 @default.
• W2002160983 hasConceptScore W2002160983C98274493 @default.
• W2002160983 hasIssue "3" @default.

• next