Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002163904> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2002163904 abstract "The cell membrane permeability governs the rate of solute transport into and out of the cell, significantly affecting the cell's metabolic processes, viability, and potential usefulness in both biotechnological applications and physiological systems. Most previous studies of the cell membrane permeability have neglected the possible effects of suspending medium on membrane transport, even though there is extensive experimental evidence that suspending phase composition can significantly affect other properties related to the cell membrane (e.g., cell deformability, fragility, and aggregation rate). This study examined the effects of suspending phase composition (both proteins and electrolytes) on the permeability of human red blood cells to the metabolites creatinine and uric acid. Data were obtained using a stirred ultrafiltration device with direct cell- and proteinfree sampling through a semipermeable membrane. Both the uric acid and creatinine permeabilities were strongly affected by the suspending phase composition, with the permeabilities in different buffer solutions varying by as much as a factor of three. The predominant factors affecting the permeability were the presence (or absence) of chloride, phosphate/adenine, and proteins, although the magnitude and even the direction of these effects were significantly different for creatinine and uric acid transport. The dramatic differences in behavior for uric acid and creatinine reflect the different transport mechanisms for these solutes, with uric acid transported by a carrier-mediated mechanism and creatinine transported by passive diffusion through the lipid bilayer. These results provide important insights into the effects of solution environment on cell membrane transport and other cell membrane-mediated properties." @default.
- W2002163904 created "2016-06-24" @default.
- W2002163904 creator A5012067314 @default.
- W2002163904 creator A5017353021 @default.
- W2002163904 date "1994-01-20" @default.
- W2002163904 modified "2023-09-27" @default.
- W2002163904 title "Effect of solution environment on the permeability of red blood cells" @default.
- W2002163904 cites W1504110941 @default.
- W2002163904 cites W1992276875 @default.
- W2002163904 cites W1996224094 @default.
- W2002163904 cites W2014289299 @default.
- W2002163904 cites W2035273702 @default.
- W2002163904 cites W2046529642 @default.
- W2002163904 cites W2051831683 @default.
- W2002163904 cites W2052618712 @default.
- W2002163904 cites W2056409867 @default.
- W2002163904 cites W2065458293 @default.
- W2002163904 cites W2159983546 @default.
- W2002163904 cites W2397605546 @default.
- W2002163904 cites W2440650847 @default.
- W2002163904 cites W3022028269 @default.
- W2002163904 cites W4211084475 @default.
- W2002163904 cites W4235004878 @default.
- W2002163904 doi "https://doi.org/10.1002/bit.260430203" @default.
- W2002163904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18615604" @default.
- W2002163904 hasPublicationYear "1994" @default.
- W2002163904 type Work @default.
- W2002163904 sameAs 2002163904 @default.
- W2002163904 citedByCount "5" @default.
- W2002163904 countsByYear W20021639042015 @default.
- W2002163904 countsByYear W20021639042019 @default.
- W2002163904 crossrefType "journal-article" @default.
- W2002163904 hasAuthorship W2002163904A5012067314 @default.
- W2002163904 hasAuthorship W2002163904A5017353021 @default.
- W2002163904 hasConcept C107511713 @default.
- W2002163904 hasConcept C120882062 @default.
- W2002163904 hasConcept C12554922 @default.
- W2002163904 hasConcept C185592680 @default.
- W2002163904 hasConcept C2779881121 @default.
- W2002163904 hasConcept C2992270614 @default.
- W2002163904 hasConcept C41625074 @default.
- W2002163904 hasConcept C43617362 @default.
- W2002163904 hasConcept C55493867 @default.
- W2002163904 hasConcept C86803240 @default.
- W2002163904 hasConceptScore W2002163904C107511713 @default.
- W2002163904 hasConceptScore W2002163904C120882062 @default.
- W2002163904 hasConceptScore W2002163904C12554922 @default.
- W2002163904 hasConceptScore W2002163904C185592680 @default.
- W2002163904 hasConceptScore W2002163904C2779881121 @default.
- W2002163904 hasConceptScore W2002163904C2992270614 @default.
- W2002163904 hasConceptScore W2002163904C41625074 @default.
- W2002163904 hasConceptScore W2002163904C43617362 @default.
- W2002163904 hasConceptScore W2002163904C55493867 @default.
- W2002163904 hasConceptScore W2002163904C86803240 @default.
- W2002163904 hasLocation W20021639041 @default.
- W2002163904 hasLocation W20021639042 @default.
- W2002163904 hasOpenAccess W2002163904 @default.
- W2002163904 hasPrimaryLocation W20021639041 @default.
- W2002163904 hasRelatedWork W1977162537 @default.
- W2002163904 hasRelatedWork W1987686354 @default.
- W2002163904 hasRelatedWork W1987814913 @default.
- W2002163904 hasRelatedWork W1989504686 @default.
- W2002163904 hasRelatedWork W1990311767 @default.
- W2002163904 hasRelatedWork W1991481157 @default.
- W2002163904 hasRelatedWork W2037746069 @default.
- W2002163904 hasRelatedWork W2047555878 @default.
- W2002163904 hasRelatedWork W2057440019 @default.
- W2002163904 hasRelatedWork W2061450883 @default.
- W2002163904 hasRelatedWork W2071602563 @default.
- W2002163904 hasRelatedWork W2088247505 @default.
- W2002163904 hasRelatedWork W2093411827 @default.
- W2002163904 hasRelatedWork W2128114205 @default.
- W2002163904 hasRelatedWork W2129640989 @default.
- W2002163904 hasRelatedWork W2143109495 @default.
- W2002163904 hasRelatedWork W2149831731 @default.
- W2002163904 hasRelatedWork W2169662236 @default.
- W2002163904 hasRelatedWork W2202915798 @default.
- W2002163904 hasRelatedWork W2416882772 @default.
- W2002163904 isParatext "false" @default.
- W2002163904 isRetracted "false" @default.
- W2002163904 magId "2002163904" @default.
- W2002163904 workType "article" @default.