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- W2002166154 abstract "Eleven chronic schizophrenic patients with abnormal skin pigmentation associated with neuroleptic treatment were withdrawn from chlorpromazine (CPZ), which was replaced by levomepromazine (n = 4), trifluoperazine (n = 1) or thioproperazine (n = 1) as the sole neuroleptic, by a combination of these phenothiazines (n = 4) or with haloperidol plus pipotiazine (n = 1). Seven patients showed complete resolution of abnormal skin pigmentation over a period of 1-5 years and 4 markedly improved over 2.0-2.6 years of follow-up. Our observations suggest that neuroleptic-induced abnormal skin pigmentation is (i) predominantly, if not exclusively, a side effect of CPZ and (ii) reversible, providing that CPZ is withdrawn and sufficient time is allowed to elapse." @default.
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- W2002166154 date "1993-03-01" @default.
- W2002166154 modified "2023-09-26" @default.
- W2002166154 title "Resolution of chlorpromazine-induced cutaneous pigmentation following substitution with levomepromazine or other neuroleptics" @default.
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- W2002166154 doi "https://doi.org/10.1111/j.1600-0447.1993.tb03360.x" @default.
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