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- W2002174883 abstract "Prolyl and lysyl hydroxylase activities in cultures of human skin fibroblasts from fetal to 94-yr-old donors were measured. In contrast to earlier studies with whole skin, neither prolyl nor lysyl hydroxylase activity was found related to donor age. Prolyl hydroxylase activity increased 3- to 6-fold when cell extracts were incubated with ascorbate and other hydroxylation cofactors before assay. A similar increase in prolyl hydroxylase activity occurred when cells were incubated with ascorbate. Lysyl hydroxylase activity remained unaltered under these conditions." @default.
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- W2002174883 date "1980-11-01" @default.
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- W2002174883 title "Prolyl and Lysyl Hydroxylase Activities of Human Skin Fibroblasts: Effects of Donor Age and Ascorbate" @default.
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- W2002174883 doi "https://doi.org/10.1111/1523-1747.ep12523660" @default.
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