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• W2002176296 abstract "La prévalence du foramen ovale perméable (FOP) est élevée, estimée à 25 % de la population générale à partir de séries autopsiques. Anatomiquement, le FOP est un tunnel qui ne peut s’ouvrir que dans le sens droit-gauche. Potentiellement responsable d’un passage intracardiaque de sang veineux dans le sang artériel systémique, le FOP peut s’accompagner d’une hypoxémie. La plupart du temps, les courts-circuits droit-gauche à travers le FOP sont transitoires et sans retentissement clinique. La présence d’une hypertension pulmonaire (HTP) peut inverser le gradient de pression gauche-droit et générer un passage de sang veineux, à travers le FOP. Toute augmentation majeure des pressions dans les cavités droites, même sans HTP, peut s’accompagner d’une réouverture du foramen ovale. Enfin, il existe d’autres situations où le passage de sang à travers le FOP serait généré par une modification de la direction des flux du retour veineux. Les shunts droit-gauches sans élévation des pressions droites sont le plus souvent intermittents, voire dépendants de la posture. Ils sont plus difficiles à mettre en évidence. The prevalence of patent foramen ovale (PFO) is high. As identified at autopsy it is found in approximately 25% of the general population. Anatomically a PFO represents a channel through which unidirectional blood flow from the right to the left atrium may occur. This potential interatrial shunt of unoxygenated venous blood into the oxygenated arterial system may lead to hypoxaemia. Usually right to left shunting across a PFO is transient and without clinical significance. Increased pulmonary arterial pressure may give rise to left-right pressure gradient reversal and right to left shunting across a PFO. High pressure in the right heart chambers, even without pulmonary arterial hypertension, can potentially lead to the reopening of a foramen ovale. In other cases inferior vena cava flow deviation might lead to right to left shunting across a PFO. Right to left shunting without pressure increase inside the right heart chambers is usually transient and even positional and its diagnosis is more difficult." @default.
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• W2002176296 date "2011-10-01" @default.
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• W2002176296 title "Foramen ovale perméable et hypoxémie avec ou sans élévation des pressions droites" @default.
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• W2002176296 doi "https://doi.org/10.1016/j.rmr.2011.07.001" @default.
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