FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002178143> ?p ?o ?g. }

• W2002178143 endingPage "7472" @default.
• W2002178143 startingPage "7467" @default.
• W2002178143 abstract "During early morphogenesis, tissue segregation is often accompanied by changes in cell shape. To understand how such coordination is regulated, somitogenesis was used as a model. When a somite forms in the anterior end of the presomitic mesoderm, an intersomitic boundary (gap) emerges, and it is rapidly followed by cell epithelialization at this border. It has been known that the gap formation is regulated by intercellular signals. We here demonstrate that cMeso-1, the chicken homolog of mouse Mesp2, up-regulates EphA4 in the cells located posteriorly to a forming boundary. This in turn activates EphrinB2-reverse signals in the anteriorly juxtaposed cells, where the EphrinB2 signal is sufficient to cause a gap formation and cell epithelialization cell-autonomously. During these processes, Cdc42 needs to be repressed via tyrosine phosphorylation of EphrinB2. This is the first demonstration that Ephrin-reverse signal acts as a platform that couples distinct morphogenetic changes in cell polarity and tissue shape." @default.
• W2002178143 created "2016-06-24" @default.
• W2002178143 creator A5003402825 @default.
• W2002178143 creator A5032787233 @default.
• W2002178143 creator A5038536046 @default.
• W2002178143 creator A5061957454 @default.
• W2002178143 creator A5066555365 @default.
• W2002178143 date "2009-05-05" @default.
• W2002178143 modified "2023-10-16" @default.
• W2002178143 title "EphrinB2 coordinates the formation of a morphological boundary and cell epithelialization during somite segmentation" @default.
• W2002178143 cites W1485965660 @default.
• W2002178143 cites W1524475817 @default.
• W2002178143 cites W1960862471 @default.
• W2002178143 cites W1969054485 @default.
• W2002178143 cites W1973160382 @default.
• W2002178143 cites W1973619153 @default.
• W2002178143 cites W1977393834 @default.
• W2002178143 cites W1993000387 @default.
• W2002178143 cites W1995691453 @default.
• W2002178143 cites W2001281468 @default.
• W2002178143 cites W2011979772 @default.
• W2002178143 cites W2020206552 @default.
• W2002178143 cites W2035317074 @default.
• W2002178143 cites W2043508733 @default.
• W2002178143 cites W2046748256 @default.
• W2002178143 cites W2048189081 @default.
• W2002178143 cites W2056790196 @default.
• W2002178143 cites W2060913542 @default.
• W2002178143 cites W2073554410 @default.
• W2002178143 cites W2080232808 @default.
• W2002178143 cites W2097276145 @default.
• W2002178143 cites W2100758852 @default.
• W2002178143 cites W2112376567 @default.
• W2002178143 cites W2124713665 @default.
• W2002178143 cites W2127619526 @default.
• W2002178143 cites W2131412906 @default.
• W2002178143 cites W2132956628 @default.
• W2002178143 cites W2151299688 @default.
• W2002178143 cites W2159360172 @default.
• W2002178143 cites W2315478064 @default.
• W2002178143 cites W2805806037 @default.
• W2002178143 cites W7846284 @default.
• W2002178143 doi "https://doi.org/10.1073/pnas.0902859106" @default.
• W2002178143 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2678603" @default.
• W2002178143 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19380726" @default.
• W2002178143 hasPublicationYear "2009" @default.
• W2002178143 type Work @default.
• W2002178143 sameAs 2002178143 @default.
• W2002178143 citedByCount "81" @default.
• W2002178143 countsByYear W20021781432012 @default.
• W2002178143 countsByYear W20021781432013 @default.
• W2002178143 countsByYear W20021781432014 @default.
• W2002178143 countsByYear W20021781432015 @default.
• W2002178143 countsByYear W20021781432016 @default.
• W2002178143 countsByYear W20021781432017 @default.
• W2002178143 countsByYear W20021781432018 @default.
• W2002178143 countsByYear W20021781432019 @default.
• W2002178143 countsByYear W20021781432020 @default.
• W2002178143 countsByYear W20021781432021 @default.
• W2002178143 countsByYear W20021781432022 @default.
• W2002178143 countsByYear W20021781432023 @default.
• W2002178143 crossrefType "journal-article" @default.
• W2002178143 hasAuthorship W2002178143A5003402825 @default.
• W2002178143 hasAuthorship W2002178143A5032787233 @default.
• W2002178143 hasAuthorship W2002178143A5038536046 @default.
• W2002178143 hasAuthorship W2002178143A5061957454 @default.
• W2002178143 hasAuthorship W2002178143A5066555365 @default.
• W2002178143 hasBestOaLocation W20021781431 @default.
• W2002178143 hasConcept C104317684 @default.
• W2002178143 hasConcept C105702510 @default.
• W2002178143 hasConcept C122428330 @default.
• W2002178143 hasConcept C145103041 @default.
• W2002178143 hasConcept C1491633281 @default.
• W2002178143 hasConcept C16693951 @default.
• W2002178143 hasConcept C196843134 @default.
• W2002178143 hasConcept C2779018604 @default.
• W2002178143 hasConcept C2780915607 @default.
• W2002178143 hasConcept C40692019 @default.
• W2002178143 hasConcept C54355233 @default.
• W2002178143 hasConcept C79879829 @default.
• W2002178143 hasConcept C86803240 @default.
• W2002178143 hasConcept C87073359 @default.
• W2002178143 hasConcept C95444343 @default.
• W2002178143 hasConceptScore W2002178143C104317684 @default.
• W2002178143 hasConceptScore W2002178143C105702510 @default.
• W2002178143 hasConceptScore W2002178143C122428330 @default.
• W2002178143 hasConceptScore W2002178143C145103041 @default.
• W2002178143 hasConceptScore W2002178143C1491633281 @default.
• W2002178143 hasConceptScore W2002178143C16693951 @default.
• W2002178143 hasConceptScore W2002178143C196843134 @default.
• W2002178143 hasConceptScore W2002178143C2779018604 @default.
• W2002178143 hasConceptScore W2002178143C2780915607 @default.
• W2002178143 hasConceptScore W2002178143C40692019 @default.
• W2002178143 hasConceptScore W2002178143C54355233 @default.
• W2002178143 hasConceptScore W2002178143C79879829 @default.
• W2002178143 hasConceptScore W2002178143C86803240 @default.
• W2002178143 hasConceptScore W2002178143C87073359 @default.
• W2002178143 hasConceptScore W2002178143C95444343 @default.

• next