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- W2002198019 abstract "Pulmonary embolism (PE) is often overlooked. If the physician maintains a high level of suspicion, the diagnosis (or its exclusion) usually becomes clarified. The ventilation/perfusion lung scan remains the primary noninvasive diagnostic test. Since the conclusion of the Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED), criteria for the ventilation/perfusion lung scan or perfusion scan alone have been strengthened. Contrast-enhanced spiral computed tomography appears to have potential, but it is not yet fully tested. Magnetic resonance angiography is in the early stages of investigation. A strategy of diagnosis based on a combination of ventilation/perfusion lung scans and serial noninvasive leg tests for deep venous thrombosis may spare the patient the costs, risks, and discomforts of pulmonary angiography. Treatment of PE is primarily anticoagulation. Low-molecular-weight heparins for the initial period of anticoagulation appear to be efficacious, easier to use than unfractionated heparin, and associated with less heparin-induced thrombocytopenia. Thrombolytic therapy, in the opinion of most investigators, should be reserved for unstable patients or patients who remain hypoxic while receiving oxygen. Catheter-tip fragmentation of the embolus occasionally is accomplished successfully." @default.
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- W2002198019 date "1998-10-01" @default.
- W2002198019 modified "2023-10-18" @default.
- W2002198019 title "Acute pulmonary embolism" @default.
- W2002198019 doi "https://doi.org/10.1097/00075198-199810000-00010" @default.
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