FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002198070> ?p ?o ?g. }

• W2002198070 endingPage "1477" @default.
• W2002198070 startingPage "1469" @default.
• W2002198070 abstract "In the neonatal rabbit kidney nephrogenesis is not yet terminated. The ampullar collecting duct epithelium acts as an inducer that generates the nephron anlagen, however, to date the morphogenic mechanisms involved are unknown. A presupposition for successful nephron induction is the close tissue interaction between the basal aspect of the ampullar collecting duct epithelium and the surrounding mesenchyme. To gain new insights in this area we raised monoclonal antibodies (mabs), to identify specific structures localized at the tissue interface. With the generated mab CDAmp1 we found an intensive immunohistochemical reaction between the basal aspect of the ampullar collecting duct epithelium and the mesenchyme. The label was most concentrated at the ampullar tip and continuously decreased in the shaft region. In the maturing collecting duct of the neonatal kidney and in the adult renal collecting duct no immunohistochemical reaction was found. The binding pattern of mab CDAmp1 is different from that of all known collecting duct cell markers and from antibodies against known basement membrane compounds such as laminin or collagen type IV. Under in vitro conditions immunoreactivity with mab CDAmp1 was obtained using embryonic collecting duct epithelia and perfusion culture. The antigen was present in specimens treated with Iscove's modified Dulbecco's Medium (IMDM) containing 10% fetal bovine serum. Omittance of serum or hormonal treatment with aldosterone, insulin or vitamin D3 led to the disappearance of the newly detected antigen, while characteristics of the differentiated collecting duct cells were up-regulated. We conclude that the expression of PCDAmp1 is a characteristic feature of the embryonic parts of the collecting duct epithelium. It may play a pivotal role during nephron induction." @default.
• W2002198070 created "2016-06-24" @default.
• W2002198070 creator A5023721241 @default.
• W2002198070 creator A5034411268 @default.
• W2002198070 creator A5038741980 @default.
• W2002198070 creator A5056759428 @default.
• W2002198070 creator A5075938477 @default.
• W2002198070 date "1997-12-01" @default.
• W2002198070 modified "2023-09-29" @default.
• W2002198070 title "PCDAmpl, a new antigen at the interface of the embryonic collecting duct epithelium and the nephrogenic mesenchyme" @default.
• W2002198070 cites W1531946526 @default.
• W2002198070 cites W1983680523 @default.
• W2002198070 cites W1991760813 @default.
• W2002198070 cites W1996105842 @default.
• W2002198070 cites W2003481405 @default.
• W2002198070 cites W2003673384 @default.
• W2002198070 cites W2010138766 @default.
• W2002198070 cites W2027152217 @default.
• W2002198070 cites W2030522563 @default.
• W2002198070 cites W2037539011 @default.
• W2002198070 cites W2057770387 @default.
• W2002198070 cites W2062804055 @default.
• W2002198070 cites W2076527625 @default.
• W2002198070 cites W2077488038 @default.
• W2002198070 cites W2084715167 @default.
• W2002198070 cites W2094410705 @default.
• W2002198070 cites W2100837269 @default.
• W2002198070 cites W2134894529 @default.
• W2002198070 cites W2149388963 @default.
• W2002198070 cites W2154427904 @default.
• W2002198070 cites W2166007950 @default.
• W2002198070 cites W2416963006 @default.
• W2002198070 cites W4250831108 @default.
• W2002198070 doi "https://doi.org/10.1038/ki.1997.477" @default.
• W2002198070 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9407492" @default.
• W2002198070 hasPublicationYear "1997" @default.
• W2002198070 type Work @default.
• W2002198070 sameAs 2002198070 @default.
• W2002198070 citedByCount "20" @default.
• W2002198070 countsByYear W20021980702014 @default.
• W2002198070 countsByYear W20021980702022 @default.
• W2002198070 crossrefType "journal-article" @default.
• W2002198070 hasAuthorship W2002198070A5023721241 @default.
• W2002198070 hasAuthorship W2002198070A5034411268 @default.
• W2002198070 hasAuthorship W2002198070A5038741980 @default.
• W2002198070 hasAuthorship W2002198070A5056759428 @default.
• W2002198070 hasAuthorship W2002198070A5075938477 @default.
• W2002198070 hasBestOaLocation W20021980701 @default.
• W2002198070 hasConcept C105702510 @default.
• W2002198070 hasConcept C126322002 @default.
• W2002198070 hasConcept C134018914 @default.
• W2002198070 hasConcept C142724271 @default.
• W2002198070 hasConcept C189165786 @default.
• W2002198070 hasConcept C203014093 @default.
• W2002198070 hasConcept C204232928 @default.
• W2002198070 hasConcept C2776193487 @default.
• W2002198070 hasConcept C2776340970 @default.
• W2002198070 hasConcept C2779814568 @default.
• W2002198070 hasConcept C2780091579 @default.
• W2002198070 hasConcept C2780186670 @default.
• W2002198070 hasConcept C2781212128 @default.
• W2002198070 hasConcept C2781231759 @default.
• W2002198070 hasConcept C529295009 @default.
• W2002198070 hasConcept C71924100 @default.
• W2002198070 hasConcept C86803240 @default.
• W2002198070 hasConcept C95444343 @default.
• W2002198070 hasConceptScore W2002198070C105702510 @default.
• W2002198070 hasConceptScore W2002198070C126322002 @default.
• W2002198070 hasConceptScore W2002198070C134018914 @default.
• W2002198070 hasConceptScore W2002198070C142724271 @default.
• W2002198070 hasConceptScore W2002198070C189165786 @default.
• W2002198070 hasConceptScore W2002198070C203014093 @default.
• W2002198070 hasConceptScore W2002198070C204232928 @default.
• W2002198070 hasConceptScore W2002198070C2776193487 @default.
• W2002198070 hasConceptScore W2002198070C2776340970 @default.
• W2002198070 hasConceptScore W2002198070C2779814568 @default.
• W2002198070 hasConceptScore W2002198070C2780091579 @default.
• W2002198070 hasConceptScore W2002198070C2780186670 @default.
• W2002198070 hasConceptScore W2002198070C2781212128 @default.
• W2002198070 hasConceptScore W2002198070C2781231759 @default.
• W2002198070 hasConceptScore W2002198070C529295009 @default.
• W2002198070 hasConceptScore W2002198070C71924100 @default.
• W2002198070 hasConceptScore W2002198070C86803240 @default.
• W2002198070 hasConceptScore W2002198070C95444343 @default.
• W2002198070 hasIssue "6" @default.
• W2002198070 hasLocation W20021980701 @default.
• W2002198070 hasLocation W20021980702 @default.
• W2002198070 hasOpenAccess W2002198070 @default.
• W2002198070 hasPrimaryLocation W20021980701 @default.
• W2002198070 hasRelatedWork W2002198070 @default.
• W2002198070 hasRelatedWork W2006704928 @default.
• W2002198070 hasRelatedWork W2041681732 @default.
• W2002198070 hasRelatedWork W2046890380 @default.
• W2002198070 hasRelatedWork W2091063299 @default.
• W2002198070 hasRelatedWork W2146979628 @default.
• W2002198070 hasRelatedWork W2150699722 @default.
• W2002198070 hasRelatedWork W2367221407 @default.
• W2002198070 hasRelatedWork W2425887252 @default.

• next