FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002202509> ?p ?o ?g. }

• W2002202509 endingPage "e1549" @default.
• W2002202509 startingPage "e1549" @default.
• W2002202509 abstract "Recognising the burden helminth infections impose on human populations, and particularly the poor, major intervention programmes have been launched to control onchocerciasis, lymphatic filariasis, soil-transmitted helminthiases, schistosomiasis, and cysticercosis. The Disease Reference Group on Helminth Infections (DRG4), established in 2009 by the Special Programme for Research and Training in Tropical Diseases (TDR), was given the mandate to review helminthiases research and identify research priorities and gaps. A summary of current helminth control initiatives is presented and available tools are described. Most of these programmes are highly dependent on mass drug administration (MDA) of anthelmintic drugs (donated or available at low cost) and require annual or biannual treatment of large numbers of at-risk populations, over prolonged periods of time. The continuation of prolonged MDA with a limited number of anthelmintics greatly increases the probability that drug resistance will develop, which would raise serious problems for continuation of control and the achievement of elimination. Most initiatives have focussed on a single type of helminth infection, but recognition of co-endemicity and polyparasitism is leading to more integration of control. An understanding of the implications of control integration for implementation, treatment coverage, combination of pharmaceuticals, and monitoring is needed. To achieve the goals of morbidity reduction or elimination of infection, novel tools need to be developed, including more efficacious drugs, vaccines, and/or antivectorial agents, new diagnostics for infection and assessment of drug efficacy, and markers for possible anthelmintic resistance. In addition, there is a need for the development of new formulations of some existing anthelmintics (e.g., paediatric formulations). To achieve ultimate elimination of helminth parasites, treatments for the above mentioned helminthiases, and for taeniasis and food-borne trematodiases, will need to be integrated with monitoring, education, sanitation, access to health services, and where appropriate, vector control or reduction of the parasite reservoir in alternative hosts. Based on an analysis of current knowledge gaps and identification of priorities, a research and development agenda for intervention tools considered necessary for control and elimination of human helminthiases is presented, and the challenges to be confronted are discussed." @default.
• W2002202509 created "2016-06-24" @default.
• W2002202509 creator A5004667433 @default.
• W2002202509 creator A5037244623 @default.
• W2002202509 creator A5046286797 @default.
• W2002202509 creator A5055957305 @default.
• W2002202509 creator A5058575981 @default.
• W2002202509 creator A5063396041 @default.
• W2002202509 creator A5073368410 @default.
• W2002202509 creator A5078281541 @default.
• W2002202509 date "2012-04-24" @default.
• W2002202509 modified "2023-10-17" @default.
• W2002202509 title "A Research Agenda for Helminth Diseases of Humans: Intervention for Control and Elimination" @default.
• W2002202509 cites W109841753 @default.
• W2002202509 cites W134451788 @default.
• W2002202509 cites W1520664895 @default.
• W2002202509 cites W1552682875 @default.
• W2002202509 cites W1802120668 @default.
• W2002202509 cites W1911493407 @default.
• W2002202509 cites W1934141242 @default.
• W2002202509 cites W1963767998 @default.
• W2002202509 cites W1964488322 @default.
• W2002202509 cites W1965200390 @default.
• W2002202509 cites W1967285730 @default.
• W2002202509 cites W1971964167 @default.
• W2002202509 cites W1978825531 @default.
• W2002202509 cites W1981367337 @default.
• W2002202509 cites W1982172824 @default.
• W2002202509 cites W1983069809 @default.
• W2002202509 cites W1983766546 @default.
• W2002202509 cites W1985071501 @default.
• W2002202509 cites W1987842358 @default.
• W2002202509 cites W1988963904 @default.
• W2002202509 cites W1993564425 @default.
• W2002202509 cites W1993671352 @default.
• W2002202509 cites W1998279724 @default.
• W2002202509 cites W1998512777 @default.
• W2002202509 cites W2000454376 @default.
• W2002202509 cites W2002776062 @default.
• W2002202509 cites W2002861734 @default.
• W2002202509 cites W2003499199 @default.
• W2002202509 cites W2004755227 @default.
• W2002202509 cites W2006721041 @default.
• W2002202509 cites W2009304165 @default.
• W2002202509 cites W2009447956 @default.
• W2002202509 cites W2016331400 @default.
• W2002202509 cites W2018753422 @default.
• W2002202509 cites W2019303799 @default.
• W2002202509 cites W2019539444 @default.
• W2002202509 cites W2021190440 @default.
• W2002202509 cites W2021603013 @default.
• W2002202509 cites W2028917816 @default.
• W2002202509 cites W2030493919 @default.
• W2002202509 cites W2031306963 @default.
• W2002202509 cites W2033294362 @default.
• W2002202509 cites W2034337979 @default.
• W2002202509 cites W2035388165 @default.
• W2002202509 cites W2036960563 @default.
• W2002202509 cites W2037645437 @default.
• W2002202509 cites W2038365622 @default.
• W2002202509 cites W2038459388 @default.
• W2002202509 cites W2046993421 @default.
• W2002202509 cites W2051178759 @default.
• W2002202509 cites W2053627879 @default.
• W2002202509 cites W2053640235 @default.
• W2002202509 cites W2054970418 @default.
• W2002202509 cites W2055195559 @default.
• W2002202509 cites W2055789080 @default.
• W2002202509 cites W2056059358 @default.
• W2002202509 cites W2067190635 @default.
• W2002202509 cites W2067867409 @default.
• W2002202509 cites W2071685455 @default.
• W2002202509 cites W2073354841 @default.
• W2002202509 cites W2073795769 @default.
• W2002202509 cites W2075791080 @default.
• W2002202509 cites W2076268422 @default.
• W2002202509 cites W2076690407 @default.
• W2002202509 cites W2078477065 @default.
• W2002202509 cites W2080736290 @default.
• W2002202509 cites W2081550858 @default.
• W2002202509 cites W2084738456 @default.
• W2002202509 cites W2085236234 @default.
• W2002202509 cites W2086660909 @default.
• W2002202509 cites W2087253029 @default.
• W2002202509 cites W2091868738 @default.
• W2002202509 cites W2092922408 @default.
• W2002202509 cites W2094315264 @default.
• W2002202509 cites W2095396224 @default.
• W2002202509 cites W2097049035 @default.
• W2002202509 cites W2100013623 @default.
• W2002202509 cites W2100629206 @default.
• W2002202509 cites W2104541820 @default.
• W2002202509 cites W2106598473 @default.
• W2002202509 cites W2107506303 @default.
• W2002202509 cites W2107905656 @default.
• W2002202509 cites W2109135570 @default.
• W2002202509 cites W2109814185 @default.
• W2002202509 cites W2113491066 @default.

• next