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- W2002209784 abstract "Since COP plays a vital role in fluid shifts and in the outcome, we studied the sequential changes in COP and total protein (TP) in 33 sick infants with severe HMD. Their birth weight and gest. age ranged from 0.55 to 2.5 kgs and 24 to 36 weeks respectively. COP was measured from 0.3 ml of heparinized arterial blood on day 1,3 & 5 using Wescor colloid osmometer. TP was measured using TS meter. In addition COP of healthy preterm infants were measured for comparison. Their mean COP was 15.36±0.56. On day 1 COP in sick infants with severe HMD was significantly lower than the healthy preterm and infants c mild HMD. 8/33 infants died by day 3. COP in these infants decreased from 11.45±0.67 on day 1 to 8.8±0.8 (p<.05) prior to death inspite of colloid administration. Among survivors COP steadily increased reaching normal levels by day 5 (see table). All infants received standard amount of fluids according to weight. COP did not correlate with G.Age or B.Wt. These data (1) demonstrate that a dropping COP is a poor prognostic indicator (2) Low COP contributes to increased transcapillary exudation (3) Gradual increase in COP among survivors suggests a decreased leakage of fluid 20 to stabilization of alveoli." @default.
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- W2002209784 date "1981-04-01" @default.
- W2002209784 modified "2023-09-26" @default.
- W2002209784 title "1627 COLLOID ONCOTIC PRESSURE (COP) IN HMD" @default.
- W2002209784 doi "https://doi.org/10.1203/00006450-198104001-01644" @default.
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