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- W2002242708 abstract "Abstract A series of amino-alkylaryl-ether and thioether deriv—atives with local anesthetic activity was investigated in an IP-RP HPLC system. Good correlation was found between the retention (log k') and octanol-water partition coefficient (log P). The values of the correlation coefficients gradu—ally increased with the increasing concentration of the ion-pairing agent, sodium dodecyl sulfate (NaDS). This experience is interpreted by the similar interactions in the partition and chromatographic systems. The Alog k' and π values gener—ated from the log k' and log P values of the compounds hav—ing basic nucleus, showed also a good correlation." @default.
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- W2002242708 date "1992-09-01" @default.
- W2002242708 modified "2023-09-26" @default.
- W2002242708 title "HPLC Investigation of a Set of Local Anesthetic Aminoether Derivatives" @default.
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- W2002242708 doi "https://doi.org/10.1080/10826079208016182" @default.
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