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- W2002246502 abstract "Abstract S-Zephyr, a hydrophilic high performance cation exchanger, has been successfully used for the separation of a series of synthetic basic peptides. Due to the absence of any hydrophobic character of the support, a linear relationship was found between the retention time and the number of cationic charges. The ability to discriminate peptides according to their charge, even in case of one unit difference, are illustrated in the total separation of a series of seven peptides, which included mtr-arginine impurity derived from peptide synthesis. Preparative trials in overloading conditions were studied for each peptide to give in the best case 99.2% final purity with a dynamic sorption capacity of 18 mg per ml of sorbent." @default.
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- W2002246502 date "1992-08-01" @default.
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- W2002246502 title "High Performance Cation Exchange Chromatography of Basic Peptides" @default.
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- W2002246502 doi "https://doi.org/10.1080/10826079208016334" @default.
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