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- W2002253120 abstract "The tone of precapillary vessels is regulated by free-Ca concentrations in the myoplasm. If the concentration of Ca decreases below 10-7 M, the muscle relaxes. Maximal amplitudes of contraction are recorded [when the concentration of Ca is higher than 5 x 10–6 M. Certain aspects of Ca regulation require electrical activity of the cell membrane. To measure the electrical response under resting and active conditions, microelectrode, double-sucrose (current and voltage-clamp techniques), and single-current recording (patch-clamp) methods have been used. Measurements of membrane potential and conductance using the microelectrode method are essential to understand the property of the voltage-dependent Ca influx. It is also essential to make electrophysiological investigations for the analysis of the receptor-activated Ca influx. Excitatory junction potentials are one indicator of the activities of the pre- and postjunctional receptors as well as of the relative amount of transmitter released. Single currents have been recorded with the patch-clamp technique in isolated vascular smooth-muscle cells." @default.
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- W2002253120 date "1985-01-01" @default.
- W2002253120 modified "2023-09-26" @default.
- W2002253120 title "Electrophysiological Aspects of Regulation of Precapillary Vessel Tone in Smooth Muscles of Vascular Tissues" @default.
- W2002253120 doi "https://doi.org/10.1097/00005344-198500073-00014" @default.
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