FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002255138> ?p ?o ?g. }

• W2002255138 abstract "Alcohol and tobacco are often used together, and alcoholism is much more common among smokers compared with nonsmokers. Studies in humans suggest that nicotine (an active ingredient in cigarette smoke) can increase the consumption of alcohol. Research on rats and mice demonstrated mixed results; some studies report that nicotine increases alcohol consumption, while others show a decrease in drinking. Because cigarette smoke includes many other chemicals, these also may play a significant role in alcohol consumption. For example, 2 of these other constituents, monoamine oxidase inhibitors and acetaldehyde, increase alcohol tolerance and/or alcohol consumption in rodents. This study was designed to investigate how cigarette smoke from tobacco may modify self-administration of alcohol in adolescent C57BL/6 mice, a critical time when adolescent humans begin abusing drugs.C57BL/6 male mice (4 to 5 weeks old) were acclimated for 3 weeks to consume a 10% (w/v) alcohol solution during a 2-hour daily access in the dark. Subsequently, half the animals were exposed to cigarette smoke for 6 h/d for 16 days. The remaining animals (control) were placed in a smoke-free adjacent chamber. Immediately following the 6-hour period in the chambers, the control and smoke-exposed mice were given access to the 10% alcohol solution for 2 hours.Animals exposed to cigarette smoke for 6 h/d consumed approximately 3- to 5-fold more alcohol than the mice in the control group throughout the 16-day study. The mice in the smoke group had a blood alcohol concentration that was nearly 4-fold that of the control mice.Cigarette smoke increases alcohol consumption several fold higher than reported studies using nicotine treatment alone in adolescent rodents. Thus, this model should be useful to determine the roles of other bioactive components in cigarette smoke that may be important in the high co-abuse of smoking and alcohol consumption." @default.
• W2002255138 created "2016-06-24" @default.
• W2002255138 creator A5003046986 @default.
• W2002255138 creator A5087380248 @default.
• W2002255138 date "2012-07-24" @default.
• W2002255138 modified "2023-10-16" @default.
• W2002255138 title "Cigarette Smoke Exposure Greatly Increases Alcohol Consumption in Adolescent C57BL/6 Mice" @default.
• W2002255138 cites W1488068950 @default.
• W2002255138 cites W1966331187 @default.
• W2002255138 cites W1968678284 @default.
• W2002255138 cites W1970065508 @default.
• W2002255138 cites W1971737660 @default.
• W2002255138 cites W1972137183 @default.
• W2002255138 cites W1975885460 @default.
• W2002255138 cites W1979166352 @default.
• W2002255138 cites W1981753746 @default.
• W2002255138 cites W1984339972 @default.
• W2002255138 cites W1988165680 @default.
• W2002255138 cites W1991887673 @default.
• W2002255138 cites W2011264957 @default.
• W2002255138 cites W2011680387 @default.
• W2002255138 cites W2013217130 @default.
• W2002255138 cites W2014269281 @default.
• W2002255138 cites W2021076013 @default.
• W2002255138 cites W2026469041 @default.
• W2002255138 cites W2028658009 @default.
• W2002255138 cites W2028697771 @default.
• W2002255138 cites W2034173380 @default.
• W2002255138 cites W2042510291 @default.
• W2002255138 cites W2043442821 @default.
• W2002255138 cites W2052371132 @default.
• W2002255138 cites W2057104160 @default.
• W2002255138 cites W2059131332 @default.
• W2002255138 cites W2063654389 @default.
• W2002255138 cites W2066605654 @default.
• W2002255138 cites W2068535495 @default.
• W2002255138 cites W2079424792 @default.
• W2002255138 cites W2080862729 @default.
• W2002255138 cites W2089044034 @default.
• W2002255138 cites W2095373568 @default.
• W2002255138 cites W2101939325 @default.
• W2002255138 cites W2121603624 @default.
• W2002255138 cites W2122206323 @default.
• W2002255138 cites W2124354326 @default.
• W2002255138 cites W2124817110 @default.
• W2002255138 cites W2135679466 @default.
• W2002255138 cites W2138349568 @default.
• W2002255138 cites W2139335356 @default.
• W2002255138 cites W2143207619 @default.
• W2002255138 cites W2163309905 @default.
• W2002255138 cites W2170715261 @default.
• W2002255138 cites W2170946568 @default.
• W2002255138 cites W3019801591 @default.
• W2002255138 cites W4231795951 @default.
• W2002255138 doi "https://doi.org/10.1111/j.1530-0277.2012.01911.x" @default.
• W2002255138 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4240006" @default.
• W2002255138 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22827559" @default.
• W2002255138 hasPublicationYear "2012" @default.
• W2002255138 type Work @default.
• W2002255138 sameAs 2002255138 @default.
• W2002255138 citedByCount "18" @default.
• W2002255138 countsByYear W20022551382013 @default.
• W2002255138 countsByYear W20022551382014 @default.
• W2002255138 countsByYear W20022551382015 @default.
• W2002255138 countsByYear W20022551382016 @default.
• W2002255138 countsByYear W20022551382017 @default.
• W2002255138 countsByYear W20022551382018 @default.
• W2002255138 countsByYear W20022551382019 @default.
• W2002255138 countsByYear W20022551382020 @default.
• W2002255138 countsByYear W20022551382021 @default.
• W2002255138 crossrefType "journal-article" @default.
• W2002255138 hasAuthorship W2002255138A5003046986 @default.
• W2002255138 hasAuthorship W2002255138A5087380248 @default.
• W2002255138 hasBestOaLocation W20022551382 @default.
• W2002255138 hasConcept C126322002 @default.
• W2002255138 hasConcept C178790620 @default.
• W2002255138 hasConcept C185592680 @default.
• W2002255138 hasConcept C2777595113 @default.
• W2002255138 hasConcept C2779547902 @default.
• W2002255138 hasConcept C2780161600 @default.
• W2002255138 hasConcept C2781066024 @default.
• W2002255138 hasConcept C2993351451 @default.
• W2002255138 hasConcept C3019635848 @default.
• W2002255138 hasConcept C33070731 @default.
• W2002255138 hasConcept C42407357 @default.
• W2002255138 hasConcept C55493867 @default.
• W2002255138 hasConcept C58874564 @default.
• W2002255138 hasConcept C71924100 @default.
• W2002255138 hasConcept C86803240 @default.
• W2002255138 hasConcept C99454951 @default.
• W2002255138 hasConceptScore W2002255138C126322002 @default.
• W2002255138 hasConceptScore W2002255138C178790620 @default.
• W2002255138 hasConceptScore W2002255138C185592680 @default.
• W2002255138 hasConceptScore W2002255138C2777595113 @default.
• W2002255138 hasConceptScore W2002255138C2779547902 @default.
• W2002255138 hasConceptScore W2002255138C2780161600 @default.
• W2002255138 hasConceptScore W2002255138C2781066024 @default.
• W2002255138 hasConceptScore W2002255138C2993351451 @default.
• W2002255138 hasConceptScore W2002255138C3019635848 @default.
• W2002255138 hasConceptScore W2002255138C33070731 @default.

• next