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- W2002258906 abstract "Despite its clinical importance, the mechanism of preeclampsia is unclear; however, many believe placental pathology might be related to maternal systemic disease. If this is true, a factor which mediates information from the placenta to the maternal circulation can be hypothesized. Among a variety of such reported factors, soluble fms-like tyrosine kinase-1 (sFlt1) will be the focus of this review. The hypoxic placenta, which is commonly found in preeclampsia, produces sFlt1; furthermore, animal experiments suggest its overexpression leads to preeclampsia-like symptoms. Keywords: Preeclampsia, sFlt-1, PlGF, VEGF, hypoxia" @default.
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- W2002258906 date "2008-03-01" @default.
- W2002258906 modified "2023-09-30" @default.
- W2002258906 title "A Possible Placental Factor for Preeclampsia: sFlt-1" @default.
- W2002258906 doi "https://doi.org/10.2174/092986708783885309" @default.
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