Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002279407> ?p ?o ?g. }
- W2002279407 endingPage "723" @default.
- W2002279407 startingPage "707" @default.
- W2002279407 abstract "The objective of this review was to evaluate the association between hypoxia and oxidative damage to DNA and lipids. Evaluation criteria encompassed specificity and validation status of the biomarkers, study design, strength of the association, dose-response relationship, biological plausibility, analogous exposures, and effect modification by intervention. The collective interpretation indicates persuasive evidence from the studies in humans for an association between hypoxia and elevated levels of oxidative damage to DNA and lipids. The levels of oxidatively generated DNA lesions and lipid peroxidation products depend on both the duration and severity of the exposure to hypoxia. Largest effects are observed with exposure to hypoxia at high altitude, but other factors, including ultraviolet light, exercise, exertion, and low intake of antioxidants, might contribute to the effect observed in subjects at high altitude. Most of the animal experimental models should be interpreted with caution because the assays for assessment of lipid peroxidation products have suboptimal validity." @default.
- W2002279407 created "2016-06-24" @default.
- W2002279407 creator A5007412972 @default.
- W2002279407 creator A5016993209 @default.
- W2002279407 creator A5034937943 @default.
- W2002279407 creator A5066850019 @default.
- W2002279407 creator A5072125894 @default.
- W2002279407 date "2008-11-01" @default.
- W2002279407 modified "2023-10-17" @default.
- W2002279407 title "Hypoxia and oxidation levels of DNA and lipids in humans and animal experimental models" @default.
- W2002279407 cites W1563306114 @default.
- W2002279407 cites W1675006565 @default.
- W2002279407 cites W1836130945 @default.
- W2002279407 cites W1960095976 @default.
- W2002279407 cites W1971355916 @default.
- W2002279407 cites W1973993203 @default.
- W2002279407 cites W1977913875 @default.
- W2002279407 cites W1978870919 @default.
- W2002279407 cites W1979670591 @default.
- W2002279407 cites W1982779076 @default.
- W2002279407 cites W1986219397 @default.
- W2002279407 cites W1986853155 @default.
- W2002279407 cites W1993730892 @default.
- W2002279407 cites W1994436291 @default.
- W2002279407 cites W1995886345 @default.
- W2002279407 cites W2000977900 @default.
- W2002279407 cites W2002346300 @default.
- W2002279407 cites W2009059668 @default.
- W2002279407 cites W2014875704 @default.
- W2002279407 cites W2022958403 @default.
- W2002279407 cites W2032224311 @default.
- W2002279407 cites W2033189729 @default.
- W2002279407 cites W2036834799 @default.
- W2002279407 cites W2041621064 @default.
- W2002279407 cites W2043558141 @default.
- W2002279407 cites W2046196654 @default.
- W2002279407 cites W2048594914 @default.
- W2002279407 cites W2049755640 @default.
- W2002279407 cites W2052034749 @default.
- W2002279407 cites W2055914179 @default.
- W2002279407 cites W2060767259 @default.
- W2002279407 cites W2063295363 @default.
- W2002279407 cites W2063311700 @default.
- W2002279407 cites W2066431692 @default.
- W2002279407 cites W2067136043 @default.
- W2002279407 cites W2069833028 @default.
- W2002279407 cites W2070597848 @default.
- W2002279407 cites W2071758673 @default.
- W2002279407 cites W2074566996 @default.
- W2002279407 cites W2075583832 @default.
- W2002279407 cites W2076203177 @default.
- W2002279407 cites W2076380861 @default.
- W2002279407 cites W2076405401 @default.
- W2002279407 cites W2076553390 @default.
- W2002279407 cites W2078047263 @default.
- W2002279407 cites W2079321364 @default.
- W2002279407 cites W2084223960 @default.
- W2002279407 cites W2085652708 @default.
- W2002279407 cites W2086857121 @default.
- W2002279407 cites W2090432184 @default.
- W2002279407 cites W2090851523 @default.
- W2002279407 cites W2091741338 @default.
- W2002279407 cites W2099169510 @default.
- W2002279407 cites W2101094594 @default.
- W2002279407 cites W2105135641 @default.
- W2002279407 cites W2105927085 @default.
- W2002279407 cites W2118242406 @default.
- W2002279407 cites W2127381835 @default.
- W2002279407 cites W2135399919 @default.
- W2002279407 cites W2137188853 @default.
- W2002279407 cites W2145329476 @default.
- W2002279407 cites W2147138564 @default.
- W2002279407 cites W2155666009 @default.
- W2002279407 cites W2157434906 @default.
- W2002279407 cites W2160090408 @default.
- W2002279407 cites W2161171605 @default.
- W2002279407 cites W2165396298 @default.
- W2002279407 cites W2169202985 @default.
- W2002279407 cites W2170919228 @default.
- W2002279407 cites W2262124469 @default.
- W2002279407 cites W2268281862 @default.
- W2002279407 cites W4238250933 @default.
- W2002279407 cites W4251619131 @default.
- W2002279407 doi "https://doi.org/10.1002/iub.109" @default.
- W2002279407 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18698611" @default.
- W2002279407 hasPublicationYear "2008" @default.
- W2002279407 type Work @default.
- W2002279407 sameAs 2002279407 @default.
- W2002279407 citedByCount "15" @default.
- W2002279407 countsByYear W20022794072012 @default.
- W2002279407 countsByYear W20022794072014 @default.
- W2002279407 countsByYear W20022794072017 @default.
- W2002279407 countsByYear W20022794072020 @default.
- W2002279407 countsByYear W20022794072021 @default.
- W2002279407 countsByYear W20022794072022 @default.
- W2002279407 crossrefType "journal-article" @default.
- W2002279407 hasAuthorship W2002279407A5007412972 @default.
- W2002279407 hasAuthorship W2002279407A5016993209 @default.