Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002298219> ?p ?o ?g. }
Showing items 1 to 56 of
56
with 100 items per page.
- W2002298219 endingPage "88" @default.
- W2002298219 startingPage "82" @default.
- W2002298219 abstract "Experiments were conducted to determine the antithiamine activity of two thiamine antagonists, dimethialium (3-[2-methyl-4-amino-5-pyrimidinyl)-methyl]-4, 5-dimethyl thiazolium nitrate) and amprolium (1-[(4-amino-2-n-propyl-5-pyrimidinyl)-methyl]-2-picolinium chloride hydrochloride) by symmetrical 5-point slope ratio assay. Thiamine activity of vitamine supplement for formula feed stored at two different temperature were also determind by 3-point slope ratio assay.After two preliminary experiments, corn-soy type diet with 5mg of thiamine•HNO3 and either 1.2g of dimethialium or 3g of amprolium per kg of diet was found to be satisfactory for the basal diet. Either growth rate or feed efficiency (gain/feed) of 10-day-old White Leghorn male chick was depressed linearly by increasing dietary levels of dimethialium up to 2.0g/kg and of amprolium up to 5.0g/kg or by decreasing dietary levels of thiamine•HNO3 to 3mg/kg of the basal diet. The linear relation ship was observed already after 7 days on the test diets. On the most deficient diet, some of the 10-day-old chicks showed slight deficiency symptoms of thiamine after 14 days, so that the experimental period was decided to be 10 to 14 days.Combined variance analysis of two 5-point slope ratio assays on dimethialium revealed that 179mg of dimethialium counterbalanced to 1mg of thiamine•HNO3 on growth rate of chicks with 95% fiducial interval between 253 to 105mg.Combined variance analysis of two 5-point slope ratio assays on amprolium revealed that 666mg of amprolium counterbalanced to 1mg of thiamine•HNO3 on growth rate of chicks with 95% fiducial interval between 848 to 484mg. Antithiamine activity of dimethialium was 3.7 times as high as that of amprolium.No significant difference of thiamine activity was observed by 3-point slope ratio assay between vitamine supplement stored at -4°C and 30°C for 5 months. The activity corresponding to 1.47 and 1.45mg of thiamine per g of supplement, respectively." @default.
- W2002298219 created "2016-06-24" @default.
- W2002298219 creator A5024749444 @default.
- W2002298219 creator A5057981859 @default.
- W2002298219 date "1969-01-01" @default.
- W2002298219 modified "2023-10-01" @default.
- W2002298219 title "Application of the slope ratio assay technique to the estimation of thiamine activity of thiamine analogues" @default.
- W2002298219 cites W2067179143 @default.
- W2002298219 doi "https://doi.org/10.2141/jpsa.6.82" @default.
- W2002298219 hasPublicationYear "1969" @default.
- W2002298219 type Work @default.
- W2002298219 sameAs 2002298219 @default.
- W2002298219 citedByCount "2" @default.
- W2002298219 countsByYear W20022982192019 @default.
- W2002298219 countsByYear W20022982192020 @default.
- W2002298219 crossrefType "journal-article" @default.
- W2002298219 hasAuthorship W2002298219A5024749444 @default.
- W2002298219 hasAuthorship W2002298219A5057981859 @default.
- W2002298219 hasBestOaLocation W20022982191 @default.
- W2002298219 hasConcept C134018914 @default.
- W2002298219 hasConcept C140793950 @default.
- W2002298219 hasConcept C185592680 @default.
- W2002298219 hasConcept C2776203871 @default.
- W2002298219 hasConcept C2778206080 @default.
- W2002298219 hasConcept C31903555 @default.
- W2002298219 hasConcept C55493867 @default.
- W2002298219 hasConcept C86803240 @default.
- W2002298219 hasConceptScore W2002298219C134018914 @default.
- W2002298219 hasConceptScore W2002298219C140793950 @default.
- W2002298219 hasConceptScore W2002298219C185592680 @default.
- W2002298219 hasConceptScore W2002298219C2776203871 @default.
- W2002298219 hasConceptScore W2002298219C2778206080 @default.
- W2002298219 hasConceptScore W2002298219C31903555 @default.
- W2002298219 hasConceptScore W2002298219C55493867 @default.
- W2002298219 hasConceptScore W2002298219C86803240 @default.
- W2002298219 hasIssue "2" @default.
- W2002298219 hasLocation W20022982191 @default.
- W2002298219 hasOpenAccess W2002298219 @default.
- W2002298219 hasPrimaryLocation W20022982191 @default.
- W2002298219 hasRelatedWork W15031174 @default.
- W2002298219 hasRelatedWork W2052265245 @default.
- W2002298219 hasRelatedWork W2098729526 @default.
- W2002298219 hasRelatedWork W2113752661 @default.
- W2002298219 hasRelatedWork W2126820512 @default.
- W2002298219 hasRelatedWork W2172136383 @default.
- W2002298219 hasRelatedWork W2313476627 @default.
- W2002298219 hasRelatedWork W2748952813 @default.
- W2002298219 hasRelatedWork W2952021465 @default.
- W2002298219 hasRelatedWork W2953078526 @default.
- W2002298219 hasVolume "6" @default.
- W2002298219 isParatext "false" @default.
- W2002298219 isRetracted "false" @default.
- W2002298219 magId "2002298219" @default.
- W2002298219 workType "article" @default.