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- W2002302488 abstract "Abstract The syntheses of three classes of adenosine analogues involving cyclosubstitution at the 6-position and functionalization at the 2-position are reported. The target molecules synthesized are stable with respect to hydrolytic deamination by mammalian adenosine deaminase, and, because of major structural changes at the 2- and 6-positions, these compounds are expected to be poor phosphorylation substrates for the kinases. Adenosine receptor binding data reveal that several of the compounds synthesized show excellent A1 receptor affinity and A2/A1 selectivity." @default.
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- W2002302488 date "1995-05-01" @default.
- W2002302488 modified "2023-09-27" @default.
- W2002302488 title "Strategically Functionalized Adenosines: Agonists for Adenosine Receptors" @default.
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- W2002302488 doi "https://doi.org/10.1080/15257779508012421" @default.
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