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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002302937> ?p ?o ?g. }

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• W2002302937 abstract "The most common mutation associated with Progressive Myoclonus Epilepsy (EPM1) of Unverricht-Lundberg type is the expansion of a dodecamer repeat, d(CCCCGCCCCGCG)n. We show that the C-rich strand of this repeat (2-3 copies) forms intercalated i-motif structure at acidic pH as judged by CD spectroscopy and anomalous gel electrophoretic mobility. The stability of the structure increases with the increase in the length of the repeat. Transient formation of stable, folded back structure like i-motif could play an important role in the mechanism of expansion of this repeat." @default.
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• W2002302937 date "2001-10-01" @default.
• W2002302937 modified "2023-10-11" @default.
• W2002302937 title "Intramolecular i-motif Structure at Acidic pH for Progressive Myoclonus Epilepsy (EPM1) Repeat d(CCCCGCCCCGCG)_n" @default.
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• W2002302937 doi "https://doi.org/10.1080/07391102.2001.10506741" @default.
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