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• W2002334263 abstract "Background: Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder in 4% - 6% of women in the reproductive age and is a common cause of infertility. Even though the number of investigations is scarce, studies show that Helicobacter pylori infection may influence reproduction. Objectives: The purpose of this study was to determine and compare the levels of H. pylori specific antibodies IgA, IgG and anti-CagA at both PCOS and non-PCOS women with their spouses using the serological test. Patients and Methods: In this cross-sectional study, 127 women with their spouses (age range, 30 - 60 years) were selected. These patient were referred to infertility center of Shariati Hospital in Tehran, Iran, with a diagnostic criteria of PCOS based on Androgen Excess Society (AES). The specific antibodies of IgA, IgG and anti-CagA were measured using the commercial Enzyme-Linked Immunosorbent Assay (ELISA) kit. Results: The positive titers of H. pylori antibodies IgA, IgG and anti-CagA in the PCOS group were 45 (35%), 79 (62%) and 77 (60.5%), respectively, while in non-PCOS group were 38 (30%), 76 (60%) and 50 (39.5%), respectively. The sera positive for IgA, IgG and anti-CagA antibodies in spouses of the non-PCOS group were 38 (30%), 84 (66%) and 79 (62%) respectively, but in spouses of the PCOS group were 51 (40%), 83 (66%) and 48 (38%), respectively. The results showed that H. pylori infection probably did not affect infertility or reproduction. Conclusions: Findings of this study demonstrate no significant difference between levels of H. pylori specific antibodies of IgA, IgG, anti-CagA and the presence of PCOS disorders, and also indicate that serologic testing is a sensitive method for the detection of H. pylori antibodies. The high prevalence of H. pylori positive antibody levels in both PCOS and non-PCOS patients can be probably associated with the high frequency of H. pylori infection." @default.
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• W2002334263 date "2015-04-22" @default.
• W2002334263 modified "2023-09-26" @default.
• W2002334263 title "Serological Diagnosis of Helicobacter pylori Infection in Patients With a Polycystic Ovary Syndrome" @default.
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• W2002334263 doi "https://doi.org/10.5812/archcid.10(2)2015.27432" @default.
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