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- W2002338610 abstract "The Na+/I- symporter (NIS) is an intrinsic plasma membrane protein that mediates the active transport of I- in the thyroid, lactating mammary gland, stomach and salivary glands. The presence of NIS in the thyroid is exploited in diagnostic scintigraphic imaging and radioiodide therapy in thyroid cancer. The continued rapid progress in NIS research (aimed at the elucidation of the Na+-dependent I- transport mechanism, the analysis of NIS structure-function relations and the study of the tissue-specific regulation of NIS at all levels), holds potentially far-reaching medical applications beyond thyroid disease, in breast cancer and malignancies in other tissues." @default.
- W2002338610 created "2016-06-24" @default.
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- W2002338610 date "2001-08-01" @default.
- W2002338610 modified "2023-10-17" @default.
- W2002338610 title "Journey of the iodide transporter NIS: from its molecular identification to its clinical role in cancer" @default.
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- W2002338610 doi "https://doi.org/10.1016/s0968-0004(01)01904-1" @default.
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