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- W2002357551 abstract "Avian myeloblastosis virus (AMV) is an oncogenic retrovirus that rapidly causes myeloblastic leukemia in chickens and transforms myeloid cells in culture. AMV carries an oncogene, v-myb, that is derived from a cellular gene, c-myb, found in the genomes of vertebrate species. We constructed a plasmid vector that allows expression of a portion of the coding region for v-myb in a procaryotic host. We then used the myb-encoded protein produced in bacteria to immunize rabbits. The antisera obtained permitted identification of the proteins encoded by both v-myb and chicken c-myb. The molecular weights of the products of v-myb and c-myb (45,000 and 75,000 respectively) indicate that the v-myb protein is an appreciably truncated version of the c-myb protein." @default.
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- W2002357551 date "1983-06-01" @default.
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- W2002357551 title "The product of the retroviral transforming gene v-myb is a truncated version of the protein encoded by the cellular oncogene c-myb" @default.
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- W2002357551 doi "https://doi.org/10.1016/0092-8674(83)90416-6" @default.
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