Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002364272> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2002364272 endingPage "126" @default.
- W2002364272 startingPage "117" @default.
- W2002364272 abstract "A quantitative assay was developed to evaluate mitogen-induced lymphoblastic transformation in beluga whales (Delphinapterus leucas) using peripheral blood mononuclear cells, splenocytes and thymocytes. Optimal concentrations of four different mitogens (Con-A, PHA, LPS and PWM) were determined with the use of standard curves. Addition of human recombinant IL-2 (rhIL-2) after 48 h in culture with the different mitogens suggests that Con-A, PHA and PWM, but not LPS, stimulate T cells in belugas, as they do in other animal species. The addition of 2-mercaptoethanol did not enhance significantly the proliferation of cells stimulated by Con-A, PHA and LPS, while it did with the cells stimulated by PWM and those cultured without mitogen. The proliferative response of cells was suppressed when the culture medium was supplemented by beluga serum instead of fetal calf serum. This assay will be useful to assess the status of the immune functions in different populations of beluga whales as well for further in vitro immunotoxicological experiments." @default.
- W2002364272 created "2016-06-24" @default.
- W2002364272 creator A5006270431 @default.
- W2002364272 creator A5019371748 @default.
- W2002364272 creator A5021447253 @default.
- W2002364272 creator A5029914934 @default.
- W2002364272 creator A5043882729 @default.
- W2002364272 creator A5046008499 @default.
- W2002364272 date "1996-03-01" @default.
- W2002364272 modified "2023-10-16" @default.
- W2002364272 title "Immune functions in beluga whales (Delphinapterus leucas): Evaluation of mitogen-induced blastic transformation of lymphocytes from peripheral blood, spleen and thymus" @default.
- W2002364272 cites W1521790066 @default.
- W2002364272 cites W1599378332 @default.
- W2002364272 cites W1988004073 @default.
- W2002364272 cites W2013236047 @default.
- W2002364272 cites W2022714642 @default.
- W2002364272 cites W2050349710 @default.
- W2002364272 cites W2078467947 @default.
- W2002364272 cites W2091149908 @default.
- W2002364272 cites W2127993631 @default.
- W2002364272 cites W2157002219 @default.
- W2002364272 doi "https://doi.org/10.1016/0165-2427(95)05490-1" @default.
- W2002364272 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9157677" @default.
- W2002364272 hasPublicationYear "1996" @default.
- W2002364272 type Work @default.
- W2002364272 sameAs 2002364272 @default.
- W2002364272 citedByCount "45" @default.
- W2002364272 countsByYear W20023642722012 @default.
- W2002364272 countsByYear W20023642722013 @default.
- W2002364272 countsByYear W20023642722014 @default.
- W2002364272 countsByYear W20023642722015 @default.
- W2002364272 countsByYear W20023642722016 @default.
- W2002364272 countsByYear W20023642722017 @default.
- W2002364272 countsByYear W20023642722018 @default.
- W2002364272 countsByYear W20023642722019 @default.
- W2002364272 countsByYear W20023642722020 @default.
- W2002364272 countsByYear W20023642722023 @default.
- W2002364272 crossrefType "journal-article" @default.
- W2002364272 hasAuthorship W2002364272A5006270431 @default.
- W2002364272 hasAuthorship W2002364272A5019371748 @default.
- W2002364272 hasAuthorship W2002364272A5021447253 @default.
- W2002364272 hasAuthorship W2002364272A5029914934 @default.
- W2002364272 hasAuthorship W2002364272A5043882729 @default.
- W2002364272 hasAuthorship W2002364272A5046008499 @default.
- W2002364272 hasConcept C137061746 @default.
- W2002364272 hasConcept C18903297 @default.
- W2002364272 hasConcept C189976730 @default.
- W2002364272 hasConcept C202751555 @default.
- W2002364272 hasConcept C203014093 @default.
- W2002364272 hasConcept C2777510941 @default.
- W2002364272 hasConcept C2778754761 @default.
- W2002364272 hasConcept C2780545260 @default.
- W2002364272 hasConcept C2780931953 @default.
- W2002364272 hasConcept C2781005381 @default.
- W2002364272 hasConcept C2910798392 @default.
- W2002364272 hasConcept C505870484 @default.
- W2002364272 hasConcept C518008717 @default.
- W2002364272 hasConcept C55493867 @default.
- W2002364272 hasConcept C86803240 @default.
- W2002364272 hasConcept C8891405 @default.
- W2002364272 hasConceptScore W2002364272C137061746 @default.
- W2002364272 hasConceptScore W2002364272C18903297 @default.
- W2002364272 hasConceptScore W2002364272C189976730 @default.
- W2002364272 hasConceptScore W2002364272C202751555 @default.
- W2002364272 hasConceptScore W2002364272C203014093 @default.
- W2002364272 hasConceptScore W2002364272C2777510941 @default.
- W2002364272 hasConceptScore W2002364272C2778754761 @default.
- W2002364272 hasConceptScore W2002364272C2780545260 @default.
- W2002364272 hasConceptScore W2002364272C2780931953 @default.
- W2002364272 hasConceptScore W2002364272C2781005381 @default.
- W2002364272 hasConceptScore W2002364272C2910798392 @default.
- W2002364272 hasConceptScore W2002364272C505870484 @default.
- W2002364272 hasConceptScore W2002364272C518008717 @default.
- W2002364272 hasConceptScore W2002364272C55493867 @default.
- W2002364272 hasConceptScore W2002364272C86803240 @default.
- W2002364272 hasConceptScore W2002364272C8891405 @default.
- W2002364272 hasIssue "1-2" @default.
- W2002364272 hasLocation W20023642721 @default.
- W2002364272 hasLocation W20023642722 @default.
- W2002364272 hasOpenAccess W2002364272 @default.
- W2002364272 hasPrimaryLocation W20023642721 @default.
- W2002364272 hasRelatedWork W1988004073 @default.
- W2002364272 hasRelatedWork W2002364272 @default.
- W2002364272 hasRelatedWork W2039868630 @default.
- W2002364272 hasRelatedWork W2162541343 @default.
- W2002364272 hasRelatedWork W2299766980 @default.
- W2002364272 hasRelatedWork W2461053378 @default.
- W2002364272 hasRelatedWork W2897989122 @default.
- W2002364272 hasRelatedWork W3034741917 @default.
- W2002364272 hasRelatedWork W3112092669 @default.
- W2002364272 hasRelatedWork W914911106 @default.
- W2002364272 hasVolume "50" @default.
- W2002364272 isParatext "false" @default.
- W2002364272 isRetracted "false" @default.
- W2002364272 magId "2002364272" @default.
- W2002364272 workType "article" @default.