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- W2002367080 abstract "Thirty-three evaluable patients who had not received prior chemotherapy were entered on a study of vincristine therapy for advanced or recurrent endometrial carcinoma. Vincristine 1.4 mg/m2 was given weekly as an i.v. bolus for 4 weeks and then every other week. There was one complete response (CR) lasting 5 months. Five patients had partial responses (PR) lasting 3-18 months. The CR+PR rate was 18% (95% confidence interval for CR+PR was 7-36%). Thirteen patients (38%) had stable disease from 2-28 months, and 14 had progressive disease. The major toxicity was neurological, with 11 patients having grade 2 or 3 peripheral neuropathy. Vincristine at this dose and schedule has modest activity, but troublesome toxicity in advanced or recurrent endometrial carcinoma." @default.
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- W2002367080 date "1993-02-01" @default.
- W2002367080 modified "2023-09-25" @default.
- W2002367080 title "A Phase II Trial of Vincristine in Advanced or Recurrent Endometrial Carcinoma A Gynecologic Oncology Group Study" @default.
- W2002367080 doi "https://doi.org/10.1097/00000421-199302000-00005" @default.
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