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- W2002415797 abstract "Management of patients with positive surgical margins after radical prostatectomy is a complex and debatable issue. It is clear, however, that many of these patients have high-risk disease characteristics. Because of a significant risk of relapse, patients with positive surgical margins and high-risk disease characteristics should be offered the option of participating in clinical trials evaluating the role of adjuvant therapy. A distinction between the concepts of adjuvant versus salvage therapy is made and the rationale for the use of androgen deprivation therapy, chemotherapy, or a combination in the adjuvant setting is discussed in the context of the on-going phase III trials in the United States." @default.
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- W2002415797 date "2009-01-01" @default.
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- W2002415797 title "Positive surgical margins: The argument for androgen deprivation and chemotherapy" @default.
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- W2002415797 doi "https://doi.org/10.1016/j.urolonc.2008.04.003" @default.
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