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- W2002434650 endingPage "1272" @default.
- W2002434650 startingPage "1265" @default.
- W2002434650 abstract "Immunoglobulin class switch recombination is directed to the same switch region on both chromosomes of a B cell by an as yet unknown mechanism. The cytokine interleukin 4 (IL4) targets recombination in activated B lymphocytes to the gamma 1 switch region (s gamma 1). Here we report two DNA-binding-proteins which bind to a sequence 5' of s gamma 1. One protein is B cell specific, while binding of the other one is induced by IL4. These two proteins bind to a region 700 bp upstream of the putative promoter region of the gamma 1 germline transcripts and may be involved in the process of recombination and/or transcription." @default.
- W2002434650 created "2016-06-24" @default.
- W2002434650 creator A5006949032 @default.
- W2002434650 creator A5016529394 @default.
- W2002434650 date "1992-10-01" @default.
- W2002434650 modified "2023-10-18" @default.
- W2002434650 title "DNA binding sites 5′ of the IgG1 switch region comprising IL4 inducibility and B cell specificity" @default.
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- W2002434650 doi "https://doi.org/10.1016/0161-5890(92)90063-4" @default.
- W2002434650 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1528195" @default.
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