Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002458980> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2002458980 endingPage "299" @default.
- W2002458980 startingPage "263" @default.
- W2002458980 abstract "Innate-like lymphocytes, which comprise an integral part of the immune system, possess unique developmental and functional capabilities that set them apart from conventional T and B lymphocytes. Strategically located to act as a first line of defense against pathogens, they behave as innate cells. To efficiently perform their innate functions, these populations are endowed with common phenotypic characteristics that include the expression of semi-invariant TCR or BCR and activation/memory cell markers. Moreover, they have the capacity to rapidly respond to pathogenic threats and the ability to ignite adaptive immune response in synchrony with myeloid cells. Indeed, all of these common features mirror a shared molecular program, in which Signaling Lymphocytic Activation Molecule Family (SLAMF) receptors and their cytoplasmic binding partner, the adapter signaling lymphocytic activation−associated protein (SAP), play a crucial role. Despite the extensive characterization of SLAMF molecules as a group of cell-surface receptors that regulate and interconnect both innate and adaptive immune cells, their relevance in innate-like lymphocyte ontogeny and physiology has recently taken center stage. Here, we review the current understanding of the roles SLAMF receptors and SAP adaptor molecules play in the biology of innate-like lymphocytes." @default.
- W2002458980 created "2016-06-24" @default.
- W2002458980 creator A5073496723 @default.
- W2002458980 creator A5083885317 @default.
- W2002458980 creator A5087395078 @default.
- W2002458980 date "2014-01-01" @default.
- W2002458980 modified "2023-10-08" @default.
- W2002458980 title "Role of SLAM Family Receptors and Specific Adapter SAP in Innate-Like Lymphocytes" @default.
- W2002458980 doi "https://doi.org/10.1615/critrevimmunol.2014010538" @default.
- W2002458980 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24941157" @default.
- W2002458980 hasPublicationYear "2014" @default.
- W2002458980 type Work @default.
- W2002458980 sameAs 2002458980 @default.
- W2002458980 citedByCount "18" @default.
- W2002458980 countsByYear W20024589802016 @default.
- W2002458980 countsByYear W20024589802017 @default.
- W2002458980 countsByYear W20024589802018 @default.
- W2002458980 countsByYear W20024589802019 @default.
- W2002458980 countsByYear W20024589802020 @default.
- W2002458980 countsByYear W20024589802021 @default.
- W2002458980 countsByYear W20024589802022 @default.
- W2002458980 countsByYear W20024589802023 @default.
- W2002458980 crossrefType "journal-article" @default.
- W2002458980 hasAuthorship W2002458980A5073496723 @default.
- W2002458980 hasAuthorship W2002458980A5083885317 @default.
- W2002458980 hasAuthorship W2002458980A5087395078 @default.
- W2002458980 hasConcept C136449434 @default.
- W2002458980 hasConcept C169760540 @default.
- W2002458980 hasConcept C170493617 @default.
- W2002458980 hasConcept C183786373 @default.
- W2002458980 hasConcept C193419808 @default.
- W2002458980 hasConcept C203014093 @default.
- W2002458980 hasConcept C54355233 @default.
- W2002458980 hasConcept C62478195 @default.
- W2002458980 hasConcept C86803240 @default.
- W2002458980 hasConcept C8891405 @default.
- W2002458980 hasConcept C95444343 @default.
- W2002458980 hasConceptScore W2002458980C136449434 @default.
- W2002458980 hasConceptScore W2002458980C169760540 @default.
- W2002458980 hasConceptScore W2002458980C170493617 @default.
- W2002458980 hasConceptScore W2002458980C183786373 @default.
- W2002458980 hasConceptScore W2002458980C193419808 @default.
- W2002458980 hasConceptScore W2002458980C203014093 @default.
- W2002458980 hasConceptScore W2002458980C54355233 @default.
- W2002458980 hasConceptScore W2002458980C62478195 @default.
- W2002458980 hasConceptScore W2002458980C86803240 @default.
- W2002458980 hasConceptScore W2002458980C8891405 @default.
- W2002458980 hasConceptScore W2002458980C95444343 @default.
- W2002458980 hasIssue "4" @default.
- W2002458980 hasLocation W20024589801 @default.
- W2002458980 hasLocation W20024589802 @default.
- W2002458980 hasOpenAccess W2002458980 @default.
- W2002458980 hasPrimaryLocation W20024589801 @default.
- W2002458980 hasRelatedWork W1175477002 @default.
- W2002458980 hasRelatedWork W1841503726 @default.
- W2002458980 hasRelatedWork W2082627135 @default.
- W2002458980 hasRelatedWork W2086739630 @default.
- W2002458980 hasRelatedWork W2141330728 @default.
- W2002458980 hasRelatedWork W2188294308 @default.
- W2002458980 hasRelatedWork W2364577086 @default.
- W2002458980 hasRelatedWork W2610389334 @default.
- W2002458980 hasRelatedWork W2884963187 @default.
- W2002458980 hasRelatedWork W3140535742 @default.
- W2002458980 hasVolume "34" @default.
- W2002458980 isParatext "false" @default.
- W2002458980 isRetracted "false" @default.
- W2002458980 magId "2002458980" @default.
- W2002458980 workType "article" @default.