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• W2002474619 abstract "Background: Correlates of ethnicity among blacks with ADHF are understudied. We assessed depressive symptoms and quality of life (QOL) in a cohort of minorities cared for at inner city hospitals with a high volume of black patients. Methods: Minnesota Living With Heart Failure Questionnaire (MLWHFQ) assessed QOL; The Patient Health Questionnaire (PHQ9) assessed depressive symptoms. Scores ≥10 on the PHQ9 identify patients with major depression. Responses of “somewhat difficult” or worse to a question about difficulty at work or home or getting along with others identify functional impairment. Hemodialysis patients, sepsis, nonenglish speakers, acute coronary syndromes, dementia were exclusion criteria. The effect of ethnicity on QOL and the contribution of depressive symptoms to overall QOL was assessed using multivariate analyses. Results: Mean age of 135 patients enrolled was 65 ± 15 years, 51% were male, mean ejection fraction (EF) was 36 ± 18%. 86% were black (n=70) or Caribbean black (n=46). Mean admit BNP was 1096 ± 1010 pg/ml. Mean MLWHFQ score was 48 ± 23, mean PHQ9 score was 9 ± 6. 47% had PHQ9 scores ≥9 (any depression); 44% scores ≥10; 19% had scores >15 (depression warranting immediate intervention). 60% had depressive symptoms causing functional impairment. Compared to patients with PHQ9 scores of ≤9, those with scores ≥10 had worse overall MLWHFQ scores: 61 ± 20 (95%CI 56-66) vs 37 ± 20 (95%CI 33-42) (p<0.0001); worse physical dimension scores 24 ± 11 (95%CI 23-28) vs 18 ± 11 (95% CI 15-21), p=0.005 and worse emotional dimension scores 12 ± 6 (95%CI 11-14) vs 4 ± 5 (95%CI 3-6), p<0.0001. Ethnicity did not predict QOL when adjusted for NYHA class, EF, gender, age, creatinine clearance and comorbidity. QOL scores and PHQ9 scores were comparable among blacks and Caribbean blacks. Depressive symptoms explained an equivalent proportion of the variance in QOL in both groups (R2 46% for blacks vs 42% for Caribbean blacks) p>0.05 Conclusions: Depressive symptoms are highly prevalent in ADHF patients cared for at centers with high volumes of black patients and account for >40% of variation in QOL in this population. Depressed patients have substantially worse QOL than previously reported in similar populations. QOL and PHQ9 scores are similar in blacks and Caribbean blacks with ADHF. Assessment of depressive symptoms is crucial in attempts at reduction in readmission rates in underserved minority populations." @default.
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• W2002474619 date "2009-08-01" @default.
• W2002474619 modified "2023-09-27" @default.
• W2002474619 title "Quality of Life and Depressive Symptoms among Minorities with Acute Decompensated Heart Failure in Hospitals Serving a Majority Black Population" @default.
• W2002474619 doi "https://doi.org/10.1016/j.cardfail.2009.06.137" @default.
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