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- W2002502289 abstract "RNA-peptide conjugates that mimic amino acid-charged tRNAs and peptidyl-tRNAs are of high importance for structural and functional investigations of ribosomal complexes. Here, we present the synthesis of glycyl-, alanyl-, and isoleucyladenosine modified solid supports that are eligible for the synthesis of stable 3'-aminoacyl- and 3'-peptidyl-tRNA termini with an amide instead of the natural ester linkage. The present work significantly expands the range of accessible peptidyl-tRNA mimics for ribosomal studies." @default.
- W2002502289 created "2016-06-24" @default.
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- W2002502289 date "2011-09-01" @default.
- W2002502289 modified "2023-10-02" @default.
- W2002502289 title "Functionalized polystyrene supports for solid-phase synthesis of glycyl-, alanyl-, and isoleucyl-RNA conjugates as hydrolysis-resistant mimics of peptidyl-tRNAs" @default.
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- W2002502289 doi "https://doi.org/10.1016/j.bmc.2011.07.018" @default.
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