Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002505909> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2002505909 endingPage "203" @default.
- W2002505909 startingPage "198" @default.
- W2002505909 abstract "To review the clinical behavior and histopathologic features of medulloblastomas that metastasize outside the central nervous systems (CNS).The authors studied 23 cases of medulloblastomas that metastasized outside the CNS. The patients included 15 males and 8 females, ages 1 to 40 years at initial diagnosis (median 8.5). Five of the patients were over 20 years of age at diagnosis. The histologic grade of anaplasia was determined for each case.Extra-CNS metastases were identified at initial presentation in four individuals and up to 11 years later in the remaining cases. Metastatic sites included bone/bone marrow (21 cases), soft tissue/lymph nodes (3 cases), and lung (1 case). In seven cases, multiple extra-CNS metastatic sites were documented. Of the patients with available clinical follow-up after metastasis, 10 died of their disease 1 to 39 months after detection of extra-CNS metastases (median 9 months), while 5 are alive 16 to 120 months after extra-CNS metastasis (median 45 months). Moderate or severe anaplasia was detected in 8 of 20 intracranial specimens (40%) and in 4 of 6 extra-CNS metastases (66%); these frequencies are higher than observed in medulloblastomas overall. Tissue from both the initial resection and subsequent recurrence or metastasis was available in six cases. The anaplasia grade was higher upon recurrence or metastasis in four of these six, consistent with tumor progression.Metastasis of medulloblastomas outside the CNS can occur after long periods of clinical remission and is associated with anaplasia in some cases. Medulloblastomas can show histologic progression on recurrence or metastasis." @default.
- W2002505909 created "2016-06-24" @default.
- W2002505909 creator A5019028542 @default.
- W2002505909 creator A5026609192 @default.
- W2002505909 creator A5052467848 @default.
- W2002505909 creator A5060842441 @default.
- W2002505909 creator A5080549544 @default.
- W2002505909 date "2003-03-01" @default.
- W2002505909 modified "2023-10-18" @default.
- W2002505909 title "Medulloblastomas With Systemic Metastases: Evaluation of Tumor Histopathology and Clinical Behavior in 23 Patients" @default.
- W2002505909 cites W1509802320 @default.
- W2002505909 cites W1607516807 @default.
- W2002505909 cites W173635123 @default.
- W2002505909 cites W1917479641 @default.
- W2002505909 cites W1929317361 @default.
- W2002505909 cites W1961139212 @default.
- W2002505909 cites W1984263811 @default.
- W2002505909 cites W1986557288 @default.
- W2002505909 cites W2000394497 @default.
- W2002505909 cites W2006755529 @default.
- W2002505909 cites W2017501183 @default.
- W2002505909 cites W2031407679 @default.
- W2002505909 cites W2045090865 @default.
- W2002505909 cites W2048242881 @default.
- W2002505909 cites W2048932011 @default.
- W2002505909 cites W2052367534 @default.
- W2002505909 cites W2070255265 @default.
- W2002505909 cites W2073584256 @default.
- W2002505909 cites W2095247959 @default.
- W2002505909 cites W2133893515 @default.
- W2002505909 cites W2148794856 @default.
- W2002505909 cites W2162966612 @default.
- W2002505909 cites W2267860343 @default.
- W2002505909 cites W2883200922 @default.
- W2002505909 cites W4296216171 @default.
- W2002505909 doi "https://doi.org/10.1097/00043426-200303000-00004" @default.
- W2002505909 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12621237" @default.
- W2002505909 hasPublicationYear "2003" @default.
- W2002505909 type Work @default.
- W2002505909 sameAs 2002505909 @default.
- W2002505909 citedByCount "56" @default.
- W2002505909 countsByYear W20025059092012 @default.
- W2002505909 countsByYear W20025059092013 @default.
- W2002505909 countsByYear W20025059092014 @default.
- W2002505909 countsByYear W20025059092015 @default.
- W2002505909 countsByYear W20025059092016 @default.
- W2002505909 countsByYear W20025059092017 @default.
- W2002505909 countsByYear W20025059092018 @default.
- W2002505909 countsByYear W20025059092020 @default.
- W2002505909 countsByYear W20025059092021 @default.
- W2002505909 countsByYear W20025059092022 @default.
- W2002505909 crossrefType "journal-article" @default.
- W2002505909 hasAuthorship W2002505909A5019028542 @default.
- W2002505909 hasAuthorship W2002505909A5026609192 @default.
- W2002505909 hasAuthorship W2002505909A5052467848 @default.
- W2002505909 hasAuthorship W2002505909A5060842441 @default.
- W2002505909 hasAuthorship W2002505909A5080549544 @default.
- W2002505909 hasConcept C121608353 @default.
- W2002505909 hasConcept C126322002 @default.
- W2002505909 hasConcept C142724271 @default.
- W2002505909 hasConcept C2779013556 @default.
- W2002505909 hasConcept C2780263296 @default.
- W2002505909 hasConcept C544855455 @default.
- W2002505909 hasConcept C71924100 @default.
- W2002505909 hasConceptScore W2002505909C121608353 @default.
- W2002505909 hasConceptScore W2002505909C126322002 @default.
- W2002505909 hasConceptScore W2002505909C142724271 @default.
- W2002505909 hasConceptScore W2002505909C2779013556 @default.
- W2002505909 hasConceptScore W2002505909C2780263296 @default.
- W2002505909 hasConceptScore W2002505909C544855455 @default.
- W2002505909 hasConceptScore W2002505909C71924100 @default.
- W2002505909 hasIssue "3" @default.
- W2002505909 hasLocation W20025059091 @default.
- W2002505909 hasLocation W20025059092 @default.
- W2002505909 hasOpenAccess W2002505909 @default.
- W2002505909 hasPrimaryLocation W20025059091 @default.
- W2002505909 hasRelatedWork W1506200166 @default.
- W2002505909 hasRelatedWork W1995515455 @default.
- W2002505909 hasRelatedWork W2063583146 @default.
- W2002505909 hasRelatedWork W2080531066 @default.
- W2002505909 hasRelatedWork W2748952813 @default.
- W2002505909 hasRelatedWork W2899084033 @default.
- W2002505909 hasRelatedWork W3031052312 @default.
- W2002505909 hasRelatedWork W3032375762 @default.
- W2002505909 hasRelatedWork W3108674512 @default.
- W2002505909 hasRelatedWork W4307845509 @default.
- W2002505909 hasVolume "25" @default.
- W2002505909 isParatext "false" @default.
- W2002505909 isRetracted "false" @default.
- W2002505909 magId "2002505909" @default.
- W2002505909 workType "article" @default.