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- W2002528709 abstract "Abstract The synthesis and accumulation of mengovirus replicative intermediate, replicative form, and single-stranded RNA proceed in an identical manner in both restrictive and productive cells for the first 4 hours after infection. Subsequent to 4-hour post-infection, total mengovirus RNA accumulation in restrictively infected MDBK ceases, whereas viral RNA accumulation in productively infected L cells and Ehrlich ascites tumor cells continues. Pulse-labeling experiments demonstrate that the synthesis of viral RNA continues beyond 4 hours after infection in MDBK at a rate equal to that in productively infected cell lines. It is concluded that the restrictive cessation in viral RNA accumulation and the limited yield of virus in MDBK result from the degradation of newly synthesized viral RNA." @default.
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- W2002528709 date "1970-09-01" @default.
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- W2002528709 title "Mengovirus RNA synthesis in productive and restrictive cell lines" @default.
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- W2002528709 doi "https://doi.org/10.1016/0042-6822(70)90240-0" @default.
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