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- W2002551165 abstract "Examination of cholecystokinin-immunoreactive cells in the rat frontal cortex revealed the presence in layers I–VI of a non-uniform population ranging in size from small to large. All were also immunoreactive for GABA. The most commonly observed dendritic form of the small cells were bipolar or bitufted although some were multipolar and demonstrated vasoactive intestinal polypeptide and a few case calretinin immunoreactivity. The large cells were multipolar or bitufted and lacked expression of vasoactive intestinal polypeptide and calretinin immunoreactivity but occasionally showed calbindin D28k immunoreactivity. Therefore, the cholecystokinin-immunoreactive cells could be divided into two distinct subpopulations depending on their chemistry andn morphology. Our previous studis showed that GABAergic cells in teh neocortex could be classified into at least three chemically different subgroups: (1) par valbumin-containing cells: (2) somatostatin-containing cells (most of them also contain calbindin D28k): and (3) vasoactive intestinal polypeptide- and/or calretinin-containing cells. The present results indicated that the small cholecystokinin-immunoreactive non-pyramidal cells constitute a subset of the vsoactive intestinal polypeptide- and/or calretinin-containing cortical GABAergic cells. The large cells remain to be categorized. kwInterneuron; VIP; Calretinin; Calbindin D28k; Co-localization" @default.
- W2002551165 created "2016-06-24" @default.
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- W2002551165 date "1997-03-01" @default.
- W2002551165 modified "2023-10-18" @default.
- W2002551165 title "Two distinct subgroups of cholecystokinin-immunoreactive cortical interneurons" @default.
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- W2002551165 doi "https://doi.org/10.1016/s0006-8993(96)01446-1" @default.
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