Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002552092> ?p ?o ?g. }
- W2002552092 endingPage "201" @default.
- W2002552092 startingPage "199" @default.
- W2002552092 abstract "The 825T allele of a common C825T polymorphism in the gene encoding the beta3 subunit of heterotrimeric G proteins is associated with enhanced activation of pertussis toxin (PTX)-sensitive G proteins. We investigated responses of human platelets upon stimulation with epinephrine, which activates PTX-sensitive G proteins, and with agonists which activate additionally, or exclusively PTX-insensitive pathways. Slopes and maximum of the secondary aggregation were significantly enhanced in platelets from 825T allele carriers after epinephrine, and after combined epinephrine/ADP. This effect was more pronounced after inhibition of the cyclooxygenase-2 pathway by acetylsalicylic acid. This phenomenon appeared independent of platelet secretion, or inhibition of the adenylyl cyclase." @default.
- W2002552092 created "2016-06-24" @default.
- W2002552092 creator A5003299152 @default.
- W2002552092 creator A5008355737 @default.
- W2002552092 creator A5012221762 @default.
- W2002552092 creator A5024020063 @default.
- W2002552092 creator A5055892417 @default.
- W2002552092 creator A5058109044 @default.
- W2002552092 creator A5061370288 @default.
- W2002552092 creator A5085262390 @default.
- W2002552092 date "2000-11-08" @default.
- W2002552092 modified "2023-09-25" @default.
- W2002552092 title "Enhanced epinephrine-induced platelet aggregation in individuals carrying the G protein β3 subunit 825T allele" @default.
- W2002552092 cites W1626322384 @default.
- W2002552092 cites W1826819713 @default.
- W2002552092 cites W1970435627 @default.
- W2002552092 cites W1998927977 @default.
- W2002552092 cites W2005443309 @default.
- W2002552092 cites W2019347876 @default.
- W2002552092 cites W2023725307 @default.
- W2002552092 cites W2025629823 @default.
- W2002552092 cites W2030625703 @default.
- W2002552092 cites W2096805701 @default.
- W2002552092 cites W2102920135 @default.
- W2002552092 cites W2106816660 @default.
- W2002552092 cites W2107164902 @default.
- W2002552092 cites W2111660129 @default.
- W2002552092 cites W2143442358 @default.
- W2002552092 cites W2160663079 @default.
- W2002552092 cites W2300369442 @default.
- W2002552092 cites W2398399785 @default.
- W2002552092 cites W2405944457 @default.
- W2002552092 doi "https://doi.org/10.1016/s0014-5793(00)02158-x" @default.
- W2002552092 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11078878" @default.
- W2002552092 hasPublicationYear "2000" @default.
- W2002552092 type Work @default.
- W2002552092 sameAs 2002552092 @default.
- W2002552092 citedByCount "38" @default.
- W2002552092 countsByYear W20025520922012 @default.
- W2002552092 countsByYear W20025520922015 @default.
- W2002552092 countsByYear W20025520922019 @default.
- W2002552092 countsByYear W20025520922020 @default.
- W2002552092 crossrefType "journal-article" @default.
- W2002552092 hasAuthorship W2002552092A5003299152 @default.
- W2002552092 hasAuthorship W2002552092A5008355737 @default.
- W2002552092 hasAuthorship W2002552092A5012221762 @default.
- W2002552092 hasAuthorship W2002552092A5024020063 @default.
- W2002552092 hasAuthorship W2002552092A5055892417 @default.
- W2002552092 hasAuthorship W2002552092A5058109044 @default.
- W2002552092 hasAuthorship W2002552092A5061370288 @default.
- W2002552092 hasAuthorship W2002552092A5085262390 @default.
- W2002552092 hasBestOaLocation W20025520921 @default.
- W2002552092 hasConcept C104292427 @default.
- W2002552092 hasConcept C104317684 @default.
- W2002552092 hasConcept C126322002 @default.
- W2002552092 hasConcept C134018914 @default.
- W2002552092 hasConcept C139407321 @default.
- W2002552092 hasConcept C153911025 @default.
- W2002552092 hasConcept C161473406 @default.
- W2002552092 hasConcept C176303035 @default.
- W2002552092 hasConcept C180754005 @default.
- W2002552092 hasConcept C185592680 @default.
- W2002552092 hasConcept C24998067 @default.
- W2002552092 hasConcept C2775859304 @default.
- W2002552092 hasConcept C2779178603 @default.
- W2002552092 hasConcept C49773422 @default.
- W2002552092 hasConcept C55493867 @default.
- W2002552092 hasConcept C62478195 @default.
- W2002552092 hasConcept C71924100 @default.
- W2002552092 hasConcept C80631254 @default.
- W2002552092 hasConcept C86803240 @default.
- W2002552092 hasConcept C89560881 @default.
- W2002552092 hasConceptScore W2002552092C104292427 @default.
- W2002552092 hasConceptScore W2002552092C104317684 @default.
- W2002552092 hasConceptScore W2002552092C126322002 @default.
- W2002552092 hasConceptScore W2002552092C134018914 @default.
- W2002552092 hasConceptScore W2002552092C139407321 @default.
- W2002552092 hasConceptScore W2002552092C153911025 @default.
- W2002552092 hasConceptScore W2002552092C161473406 @default.
- W2002552092 hasConceptScore W2002552092C176303035 @default.
- W2002552092 hasConceptScore W2002552092C180754005 @default.
- W2002552092 hasConceptScore W2002552092C185592680 @default.
- W2002552092 hasConceptScore W2002552092C24998067 @default.
- W2002552092 hasConceptScore W2002552092C2775859304 @default.
- W2002552092 hasConceptScore W2002552092C2779178603 @default.
- W2002552092 hasConceptScore W2002552092C49773422 @default.
- W2002552092 hasConceptScore W2002552092C55493867 @default.
- W2002552092 hasConceptScore W2002552092C62478195 @default.
- W2002552092 hasConceptScore W2002552092C71924100 @default.
- W2002552092 hasConceptScore W2002552092C80631254 @default.
- W2002552092 hasConceptScore W2002552092C86803240 @default.
- W2002552092 hasConceptScore W2002552092C89560881 @default.
- W2002552092 hasIssue "3" @default.
- W2002552092 hasLocation W20025520921 @default.
- W2002552092 hasLocation W20025520922 @default.
- W2002552092 hasOpenAccess W2002552092 @default.
- W2002552092 hasPrimaryLocation W20025520921 @default.
- W2002552092 hasRelatedWork W1980247498 @default.