FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002564743> ?p ?o ?g. }

• W2002564743 endingPage "2483" @default.
• W2002564743 startingPage "2474" @default.
• W2002564743 abstract "A 63-year-old male presented with fever, a subcutaneous nodule, gingival hypertrophy, lacrimal gland enlargement, and no lymphadenopathy or hepatosplenomegaly, but had anemia, thrombocytopenia, and peripheral blood (PB) plus bone marrow (BM) involvement by leukemic cells. There was minimal response to multiagent chemotherapy and local radiotherapy, with a survival of 6.5 months from disease diagnosis.The PB and/or BM leukemic cells were evaluated using electron microscopy (EM), immunohistochemistry, flow-cytometric immunophenotyping, cytochemistry, cytogenetics, Southern blot analysis for gene rearrangement and Epstein-Barr virus (EBV), polymerase chain reaction for EBV and human herpes virus-6 (HHV-6), and in vitro culturing with inducing agents.The leukemic cells were agranular and monocytoid, with a hairy cell-like bone marrow biopsy infiltrate. Myeloperoxidase (MPO) and alpha-naphthyl butyrate esterase staining was negative, and periodic acid-Schiff staining was positive by light microscopy. Electron microscopy showed MPO negativity and a lack of parallel tubular arrays. The immunophenotype was CD3-, CD56+, CD4+, CD8-, CD15+, TCR1-, and TCR2-, with germline immunoglobulin and T-cell receptor genes and an abnormal karyotype (44XY, 5q-, -13, 13q+, -15). No genomic material for EBV or HHV-6 was detected. Cell cultures with butyrate and N,N-hexamethylene bis-acetamide suggested the possible induction of tumor cells to express a T-cell immunophenotype.A case of clonal acute natural killer (NK) cell leukemia with an unusual morphology (agranular) and unique phenotype (CD3-, CD56+, CD4+, CD15+) is presented. Unlike as in other acute NK leukemias, EBV was negative; there was no evidence of HHV-6. The tumor cell, after culturing with differentiating agents, may have been induced to express a T-cell immunophenotype." @default.
• W2002564743 created "2016-06-24" @default.
• W2002564743 creator A5015247283 @default.
• W2002564743 creator A5050154369 @default.
• W2002564743 creator A5051890135 @default.
• W2002564743 creator A5055955112 @default.
• W2002564743 creator A5060881884 @default.
• W2002564743 creator A5071248597 @default.
• W2002564743 creator A5071414886 @default.
• W2002564743 creator A5075596101 @default.
• W2002564743 creator A5076873506 @default.
• W2002564743 creator A5082571324 @default.
• W2002564743 date "1995-05-15" @default.
• W2002564743 modified "2023-10-15" @default.
• W2002564743 title "Acute agranular CD4-positive natural killer cell leukemia. Comprehensive clinicopathologic studies including virologic and in vitro culture with inducing agents" @default.
• W2002564743 cites W1480061065 @default.
• W2002564743 cites W1542501019 @default.
• W2002564743 cites W1550812089 @default.
• W2002564743 cites W1756675497 @default.
• W2002564743 cites W1773256867 @default.
• W2002564743 cites W1808254916 @default.
• W2002564743 cites W1972041498 @default.
• W2002564743 cites W1982471493 @default.
• W2002564743 cites W1988252772 @default.
• W2002564743 cites W1997738890 @default.
• W2002564743 cites W2005129100 @default.
• W2002564743 cites W2009623669 @default.
• W2002564743 cites W2014176459 @default.
• W2002564743 cites W2014326940 @default.
• W2002564743 cites W2014704170 @default.
• W2002564743 cites W2027698212 @default.
• W2002564743 cites W2039497150 @default.
• W2002564743 cites W2046887582 @default.
• W2002564743 cites W2058294137 @default.
• W2002564743 cites W2065032517 @default.
• W2002564743 cites W2076207516 @default.
• W2002564743 cites W2086795402 @default.
• W2002564743 cites W2092594443 @default.
• W2002564743 cites W2103533552 @default.
• W2002564743 cites W2136488457 @default.
• W2002564743 cites W2143779946 @default.
• W2002564743 cites W2148058198 @default.
• W2002564743 cites W2259471650 @default.
• W2002564743 cites W2281319361 @default.
• W2002564743 cites W2312379741 @default.
• W2002564743 cites W2314331148 @default.
• W2002564743 cites W2316568670 @default.
• W2002564743 cites W2317497042 @default.
• W2002564743 cites W2321239824 @default.
• W2002564743 cites W2323357004 @default.
• W2002564743 cites W2335581102 @default.
• W2002564743 cites W2341603035 @default.
• W2002564743 cites W2395694643 @default.
• W2002564743 cites W2403071968 @default.
• W2002564743 cites W2407117604 @default.
• W2002564743 cites W2419043742 @default.
• W2002564743 cites W3115400937 @default.
• W2002564743 cites W3197218930 @default.
• W2002564743 doi "https://doi.org/10.1002/1097-0142(19950515)75:10<2474::aid-cncr2820751013>3.0.co;2-y" @default.
• W2002564743 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7736391" @default.
• W2002564743 hasPublicationYear "1995" @default.
• W2002564743 type Work @default.
• W2002564743 sameAs 2002564743 @default.
• W2002564743 citedByCount "112" @default.
• W2002564743 countsByYear W20025647432012 @default.
• W2002564743 countsByYear W20025647432013 @default.
• W2002564743 countsByYear W20025647432014 @default.
• W2002564743 countsByYear W20025647432015 @default.
• W2002564743 countsByYear W20025647432016 @default.
• W2002564743 countsByYear W20025647432017 @default.
• W2002564743 countsByYear W20025647432018 @default.
• W2002564743 countsByYear W20025647432019 @default.
• W2002564743 countsByYear W20025647432020 @default.
• W2002564743 countsByYear W20025647432021 @default.
• W2002564743 countsByYear W20025647432022 @default.
• W2002564743 countsByYear W20025647432023 @default.
• W2002564743 crossrefType "journal-article" @default.
• W2002564743 hasAuthorship W2002564743A5015247283 @default.
• W2002564743 hasAuthorship W2002564743A5050154369 @default.
• W2002564743 hasAuthorship W2002564743A5051890135 @default.
• W2002564743 hasAuthorship W2002564743A5055955112 @default.
• W2002564743 hasAuthorship W2002564743A5060881884 @default.
• W2002564743 hasAuthorship W2002564743A5071248597 @default.
• W2002564743 hasAuthorship W2002564743A5071414886 @default.
• W2002564743 hasAuthorship W2002564743A5075596101 @default.
• W2002564743 hasAuthorship W2002564743A5076873506 @default.
• W2002564743 hasAuthorship W2002564743A5082571324 @default.
• W2002564743 hasBestOaLocation W20025647431 @default.
• W2002564743 hasConcept C10205521 @default.
• W2002564743 hasConcept C142724271 @default.
• W2002564743 hasConcept C147483822 @default.
• W2002564743 hasConcept C153911025 @default.
• W2002564743 hasConcept C196166836 @default.
• W2002564743 hasConcept C203014093 @default.
• W2002564743 hasConcept C2776804306 @default.
• W2002564743 hasConcept C2780007613 @default.
• W2002564743 hasConcept C28328180 @default.
• W2002564743 hasConcept C54355233 @default.

• next