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- W2002581796 abstract "Facial skin temperature is higher for patients with rosacea. Papules and pustules might arise because bacteria behave differently at these warmer temperatures. We sought to: (1) compare bacteria from facial skin of patients with rosacea with that of control subjects; and (2) grow these bacteria at 30°C and 37°C to compare growth curves and secreted proteins. Bacteria isolated from pustules/skin surfaces of patients with rosacea and skin surfaces of control subjects were identified and cultured at 37°C and 30°C. Secreted proteins were separated by electrophoresis. We found that Staphylococcus epidermidis isolated from patients with rosacea was consistently β-hemolytic, whereas that from control subjects were nonhemolytic. Bacteria from patients with rosacea grew at the same rate and to the same stationary phase whether cultured at 37°C or 30°C. Isolates from patients with rosacea secreted more proteins, and generally more of each protein at 37°C compared with 30°C. In conclusion, bacteria isolated from patients with rosacea secrete different proteins and different amounts of protein at different temperatures." @default.
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- W2002581796 date "2004-02-01" @default.
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- W2002581796 title "Temperature regulates bacterial protein production: possible role in rosacea" @default.
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- W2002581796 doi "https://doi.org/10.1016/j.jaad.2003.05.005" @default.
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