Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002607031> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2002607031 endingPage "e42" @default.
- W2002607031 startingPage "e42" @default.
- W2002607031 abstract "To evaluate the efficacy and safety of add-on therapy with the phosphodiesterase type 5 inhibitor tadalafil for patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia (LUTS/BPH) treated with the α1-adrenoceptor blocker silodosin.We analyzed 103 patients with LUTS/BPH with an International Prostate Symptom Score (IPSS) of >8 after ≥4 weeks of silodosin treatment from April 2016 through December 2016 at Kori Hospital. The patients subsequently received silodosin 4.0 mg twice daily (monotherapy group) or silodosin 4.0 mg twice daily plus tadalafil 5.0 mg once daily (add-on therapy group) for 8 weeks. We assessed adverse events and evaluated the mean change from baseline to 8 weeks in the IPSS, Overactive Bladder Symptom Score (OABSS), maximum urine flow rate (Qmax), and post-void residual urine volume.Of 103 patients, 101 (98.1%) could continue medical treatment. The IPSS, OABSS, and Qmax showed significantly greater improvement in the add-on therapy than in the monotherapy group (−3.92 vs −1.24, −1.18 vs 0.10, and 1.09 vs −1.04, respectively; all P <.05). Although 4 patients experienced adverse events (add-on therapy: n = 3, 5.7%; monotherapy: n = 1, 2.0%), no significant differences were observed (P = .62). Among patients with overactive bladder (n = 55), the IPSS storage symptom subscore, IPSS urgency subscore, and OABSS urgency subscore showed significantly greater improvement in the add-on therapy than in the monotherapy group (−2.23 vs 0.17, −0.88 vs 0.28, and −1.5 vs −0.48, respectively; all P <.05).Add-on therapy with tadalafil may be effective for patients with LUTS/BPH resistant to silodosin monotherapy." @default.
- W2002607031 created "2016-06-24" @default.
- W2002607031 creator A5025730303 @default.
- W2002607031 creator A5031604218 @default.
- W2002607031 creator A5040003266 @default.
- W2002607031 creator A5040010155 @default.
- W2002607031 creator A5043283747 @default.
- W2002607031 creator A5045847158 @default.
- W2002607031 creator A5059247463 @default.
- W2002607031 creator A5064268528 @default.
- W2002607031 date "2012-05-01" @default.
- W2002607031 modified "2023-09-25" @default.
- W2002607031 title "Reply to Pascal Mouracade’s Letter to the Editor re: Rustom P. Manecksha, Ivor M. Cullen, Sarfraz Ahmad, et al. Prospective Randomised Controlled Trial Comparing Trigone-Sparing versus Trigone-Including Intradetrusor Injection of AbobotulinumtoxinA for Refractory Idiopathic Detrusor Overactivity. Eur Urol 2012;61:928–35" @default.
- W2002607031 cites W2109261025 @default.
- W2002607031 cites W2159245244 @default.
- W2002607031 doi "https://doi.org/10.1016/j.eururo.2011.12.042" @default.
- W2002607031 hasPublicationYear "2012" @default.
- W2002607031 type Work @default.
- W2002607031 sameAs 2002607031 @default.
- W2002607031 citedByCount "0" @default.
- W2002607031 crossrefType "journal-article" @default.
- W2002607031 hasAuthorship W2002607031A5025730303 @default.
- W2002607031 hasAuthorship W2002607031A5031604218 @default.
- W2002607031 hasAuthorship W2002607031A5040003266 @default.
- W2002607031 hasAuthorship W2002607031A5040010155 @default.
- W2002607031 hasAuthorship W2002607031A5043283747 @default.
- W2002607031 hasAuthorship W2002607031A5045847158 @default.
- W2002607031 hasAuthorship W2002607031A5059247463 @default.
- W2002607031 hasAuthorship W2002607031A5064268528 @default.
- W2002607031 hasConcept C121608353 @default.
- W2002607031 hasConcept C126322002 @default.
- W2002607031 hasConcept C126894567 @default.
- W2002607031 hasConcept C142724271 @default.
- W2002607031 hasConcept C197934379 @default.
- W2002607031 hasConcept C204787440 @default.
- W2002607031 hasConcept C2776235491 @default.
- W2002607031 hasConcept C2776547966 @default.
- W2002607031 hasConcept C2778941218 @default.
- W2002607031 hasConcept C2779161064 @default.
- W2002607031 hasConcept C2779478474 @default.
- W2002607031 hasConcept C2779762690 @default.
- W2002607031 hasConcept C2779929075 @default.
- W2002607031 hasConcept C2780816001 @default.
- W2002607031 hasConcept C55034048 @default.
- W2002607031 hasConcept C71924100 @default.
- W2002607031 hasConceptScore W2002607031C121608353 @default.
- W2002607031 hasConceptScore W2002607031C126322002 @default.
- W2002607031 hasConceptScore W2002607031C126894567 @default.
- W2002607031 hasConceptScore W2002607031C142724271 @default.
- W2002607031 hasConceptScore W2002607031C197934379 @default.
- W2002607031 hasConceptScore W2002607031C204787440 @default.
- W2002607031 hasConceptScore W2002607031C2776235491 @default.
- W2002607031 hasConceptScore W2002607031C2776547966 @default.
- W2002607031 hasConceptScore W2002607031C2778941218 @default.
- W2002607031 hasConceptScore W2002607031C2779161064 @default.
- W2002607031 hasConceptScore W2002607031C2779478474 @default.
- W2002607031 hasConceptScore W2002607031C2779762690 @default.
- W2002607031 hasConceptScore W2002607031C2779929075 @default.
- W2002607031 hasConceptScore W2002607031C2780816001 @default.
- W2002607031 hasConceptScore W2002607031C55034048 @default.
- W2002607031 hasConceptScore W2002607031C71924100 @default.
- W2002607031 hasIssue "5" @default.
- W2002607031 hasLocation W20026070311 @default.
- W2002607031 hasOpenAccess W2002607031 @default.
- W2002607031 hasPrimaryLocation W20026070311 @default.
- W2002607031 hasRelatedWork W1538235949 @default.
- W2002607031 hasRelatedWork W1602344923 @default.
- W2002607031 hasRelatedWork W2075661281 @default.
- W2002607031 hasRelatedWork W2419811367 @default.
- W2002607031 hasRelatedWork W2604820720 @default.
- W2002607031 hasRelatedWork W2607154394 @default.
- W2002607031 hasRelatedWork W2610354852 @default.
- W2002607031 hasRelatedWork W3083261625 @default.
- W2002607031 hasRelatedWork W4226136974 @default.
- W2002607031 hasRelatedWork W4328013121 @default.
- W2002607031 hasVolume "61" @default.
- W2002607031 isParatext "false" @default.
- W2002607031 isRetracted "false" @default.
- W2002607031 magId "2002607031" @default.
- W2002607031 workType "article" @default.