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• W2002609266 abstract "Abstract The difluoromethyl-containing Biginelli dihydropyrimidinone derivatives were synthesized by a one-pot cyclocondensation of ethyl 4,4-difluoroacetoacetate, urea, and a variety of aldehydes in the presence of 5 mol% ytterbium perfluorooctanoate [Yb(PFO) 3 ] under solvent and dehydrating agent free conditions. The comparison of reaction conditions and products was made among the different 1,3-dicarbonyl substrates (ethyl acetoacetate, ethyl 4,4-difluoroacetoacetate and ethyl 4,4,4-trifluoroacetoacetate) for the Biginelli reaction." @default.
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• W2002609266 date "2011-03-01" @default.
• W2002609266 modified "2023-09-23" @default.
• W2002609266 title "One-pot synthesis of difluoromethyl-containing dihydropyrimidinones catalyzed by Yb(PFO)3 under solvent and dehydrating agent free conditions" @default.
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• W2002609266 doi "https://doi.org/10.1016/j.jfluchem.2010.12.010" @default.
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